Studies on benzene mutagenesis. I. The micronucleus test

Experientia
M DíazJ Diez

Abstract

The mutagenic action of benzene was studied by means of the micronucleus test performed on mice. A linear dose effect relationship was found for the percentage of micronucleated erythrocytes, against the benzene-dose logarithms. A significant dose effect correlation was found either after the standard 30-h experiments or after a prolonged 54-h one. A higher effect was found in the prolonged experiments, suggesting the induction of a delay in the cell cycle by benzene.

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Citations

Dec 1, 1984·The Science of the Total Environment·L Fishbein
Mar 1, 1993·Mutation Research·M A JacksonM D Waters
May 29, 2004·Mutation Research·John WhysnerElizabeth A Lax
Jul 1, 1989·Environmental Health Perspectives·J E HuffA C Jacobs
Mar 1, 1984·Mutation Research·J A Styles, C R Richardson
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Nov 22, 2008·Toxicology and Industrial Health·S WilburO Faroon
Feb 27, 2001·Teratogenesis, Carcinogenesis, and Mutagenesis·H G RajC E Olsen

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