PMID: 702520Sep 25, 1978Paper

Studies on chloride permeability of the skin of Leptodactylus ocellatus: II. Na+ and Cl- effect of inward movements of Cl-

The Journal of Membrane Biology
C A RotunnoM Cereijido

Abstract

At low concentration (1 mM) of Cl- in the outer solution, the influx of chloride through the isolated skin (JCl13) of the South American frog Leptodactylus ocellatus (L.) seems to be carried by two mechanisms: (i) a passive one that exhibits the characteristics of an exchange diffusion process, and (ii) an active penetration. Studies of the influx and efflux of chloride (JCl13 and JCl31) indicate that the presence of a high (107 mM) concentration of Cl- in the outer solution activates the translocation of this ion through the cells. Studies of the unidirectional flux of Cl- across the outer barrier (JCl12) indicate that Na+ out stimulates the penetration of Cl- at this level. Cl- out, in turn, stimulates the JNa12, but this effect is only detected at low concentrations of Na+ out.

References

Mar 13, 1975·Biochimica Et Biophysica Acta·C O Watlington, F Jessee
Aug 20, 1971·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·F Garcia-Romeu
Oct 10, 1973·The Journal of Membrane Biology·C A RotunnoM Cereijido
Jan 1, 1973·The Journal of Membrane Biology·J H MorenoM Cereijido
Mar 1, 1972·Acta Physiologica Scandinavica·P Kristensen
Jun 1, 1970·The Journal of General Physiology·C A RotunnoM Cereijido
Apr 1, 1968·Comparative Biochemistry and Physiology·A SalibiánF García Romeu
Jun 11, 1968·Biochimica Et Biophysica Acta·K T Ferreira
Jun 1, 1966·Journal of Cellular Physiology·D W Martin, P F Curran
Jun 6, 1952·Acta Physiologica Scandinavica·V K JOHNSENH H USSING
Jan 1, 1954·Acta Physiologica Scandinavica·C B JØRGENSENK ZERAHN
Nov 1, 1963·The Journal of General Physiology·J A ZADUNAISKYD J CHIARANDINI
Mar 1, 1964·The Journal of General Physiology·B D LINDLEY, T HOSHIKO
Apr 1, 1964·Journal of Cellular Physiology·D W MARTIN
Mar 1, 1965·The Journal of General Physiology·M CEREIJIDO, P F CURRAN

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