PMID: 2491315Jan 1, 1989Paper

Studies on circulation rate and flow model for external loop bioreactor

Chinese Journal of Biotechnology
K LiuB Z Li

Abstract

We performed experiments in an external loop bioreactor 250 mm in diameter and 4500 mm in height. The variation in circulation rate Um was studied over a wide range of surface gas velocities (UG = 0-24.9 cm/s), and a bioreactor flow model was obtained. We developed a new method (i.e., an electrical conductivity tracking system) to measure circulation rate and solve the problem of measuring general circulation resistance. A theoretical formula for Um was derived for use in scaling up the bioreactor: [formula: see text]

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