PMID: 8593269Nov 1, 1995Paper

Studies on cytokines related to wound healing in donor site wound fluid

Journal of Dermatological Science
I OnoF Kaneko

Abstract

This study was performed to evaluate cytokines in donor-site wound fluids and to determine their effect on wound healing. A film dressing was applied to the donor-site wound of 24 patients immediately after a split-thickness skin graft was taken. On the 5th day after treatment, 2-3 ml of the fluid retained under the film dressing was collected by means of puncture with a syringe. Growth factors and cytokines considered to accelerate wound healing were present in relatively large amounts in the exudate. Very low concentrations of epidermal growth factor (EGF) and basic fibroblast growth factor (bFGF) were detected by a commercially-available enzyme-linked immunosorbant assay (ELISA) kit. However, the presence of both growth factors in wound fluid could not be confirmed because of the possible cross-reactivity of the antibodies to other EGF and FGF family growth factors. In contrast, platelet derived growth factor (PDGF), interleukin-6 (IL-6), transforming growth factor-alpha (TGF-alpha) and TGF-beta were present in relatively large amounts. The finding that certain cytokines coexist in a balanced state under the film dressing suggests that epithelization can proceed, since an adequate balance would insure proper regulation by th...Continue Reading

References

Nov 1, 1992·The Journal of Dermatology·K Miyazono, C H Heldin
Nov 1, 1992·The Journal of Dermatology·K Hashimoto, K Yoshikawa
Jan 1, 1992·The Journal of Investigative Dermatology·Y SarretE J O'Keefe
Nov 1, 1991·The British Journal of Surgery·A N Kingsnorth, J Slavin
Dec 1, 1991·Journal of the American Academy of Dermatology·M H KatzV Falanga
Oct 1, 1991·The Journal of Surgical Research·S C JonesG S Schultz
Jun 1, 1991·The British Journal of Dermatology·I A McKay, I M Leigh
Dec 1, 1990·The Journal of Trauma·D T CromackT A Mustoe
Jan 1, 1990·Annals of the New York Academy of Sciences·A J AmmannT A Mustoe
Jul 13, 1989·The New England Journal of Medicine·G L BrownJ B Lynch
Jun 1, 1989·Journal of Cellular Biochemistry·S M WahlN McCartney-Francis
Dec 1, 1988·Annals of Surgery·G L BrownG S Schultz
Jul 1, 1988·The Journal of Surgical Research·G S McGeeA A Demetriou
May 1, 1986·The Journal of Experimental Medicine·G L BrownG S Schultz
Nov 1, 1985·Proceedings of the National Academy of Sciences of the United States of America·A BuckleyS C Woodward
Dec 1, 1994·Scandinavian Journal of Plastic and Reconstructive Surgery and Hand Surgery·I OnoF Kaneko
Oct 1, 1993·Burns : Journal of the International Society for Burn Injuries·L S GraysonM A Nicolson
Jan 1, 1993·British Journal of Plastic Surgery·S T TanG B Blake

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Citations

Sep 22, 1999·Journal of Biomedical Materials Research·I OnoM Inoue
Jan 3, 2001·Muscle & Nerve. Supplement·D W Zochodne
Oct 3, 2007·Der Hautarzt; Zeitschrift für Dermatologie, Venerologie, und verwandte Gebiete·S A EmingT Krieg
Aug 8, 2009·Journal of Orthopaedic Science : Official Journal of the Japanese Orthopaedic Association·Akihiko TakeuchiKatsuro Tomita
Aug 1, 1995·Burns : Journal of the International Society for Burn Injuries·I OnoF Kaneko
Sep 9, 2000·Forensic Science International : Synergy·W GrellnerJ Wilske
Feb 13, 2001·Journal of Dermatological Science·I OnoT Tateshita
Sep 5, 2001·Journal of Dermatological Science·T TateshitaF Kaneko
May 25, 2002·The British Journal of Surgery·S L DrinkwaterK G Burnand
Feb 28, 2001·Diabetes, Obesity & Metabolism·J N MansbridgeG K Naughton
Sep 30, 2000·Wound Repair and Regeneration : Official Publication of the Wound Healing Society [and] the European Tissue Repair Society·L J ZhouI Ono
Sep 21, 2000·Proceedings of the Society for Experimental Biology and Medicine·A SugiharaS Ikehara
Nov 12, 2003·The Journal of Burn Care & Rehabilitation·Heather N PaddockDavid W Mozingo
Jan 10, 2008·PloS One·Aurore SchneiderChristophe Egles
Sep 29, 2011·International Journal of Molecular Sciences·Pornprom MuangmanPornanong Aramwit
Apr 13, 2010·Burns : Journal of the International Society for Burn Injuries·Yener DemirtasAhmet Demir
Apr 17, 2007·The Journal of Investigative Dermatology·Sabine WernerHans Smola
Nov 1, 2007·Wound Repair and Regeneration : Official Publication of the Wound Healing Society [and] the European Tissue Repair Society·Ichiro OnoKowichi Jimbow
Jul 26, 2007·Wound Repair and Regeneration : Official Publication of the Wound Healing Society [and] the European Tissue Repair Society·Emiko Aiba-KojimaKotaro Yoshimura
May 7, 2011·Journal of Biomedical Materials Research. Part a·Paweena UppananSiriporn Tanodekaew
Aug 17, 2005·Cytokine·Donna BryanRobin Thorpe
Jul 18, 2002·The Journal of Surgical Research·Paul A J EneverRobert T Tranquillo
Jun 17, 2008·The American Journal of Pathology·Marlon R SchneiderEckhard Wolf
May 6, 2005·The International Journal of Lower Extremity Wounds·S L DrinkwaterK G Burnand
Jun 19, 2013·The International Journal of Lower Extremity Wounds·Markus W LöfflerStefan Beckert
Oct 19, 2017·International Journal of Molecular Sciences·Dominik André-LévigneBrigitte Pittet-Cuénod
Feb 18, 2004·Physiological Genomics·Robert J FeezorDavid W Mozingo
Aug 31, 2004·World Journal of Gastroenterology : WJG·Jian-Min SiMin Gao
Jun 15, 2007·The International Journal of Lower Extremity Wounds·Magnus S Agren, Maria Werthén
May 24, 2007·Plastic and Reconstructive Surgery·Bernadette NedelecDominique R Garrel
May 14, 2005·Otology & Neurotology : Official Publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology·Akinobu KakigiTaizo Takeda

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