Studies on electrochemical oxidation of azithromycin and its interaction with bovine serum albumin

Bioelectrochemistry
Yunhua WuShengshui Hu

Abstract

A novel nanoparticle film modified electrode has been constructed using a glassy carbon electrode (GCE) coated with a carbon nanotube-dihexadecylphosphate (DHP) film. This modified electrode exhibits an enhanced effectiveness for the oxidation of azithromycin. A method is also described for the evaluation of azithromycin-bovine serum albumin (BSA) interaction. The electrochemical behavior of azithromycin as well as its interaction with BSA at this nanoparticle film electrode has been investigated by cyclic voltammetry, linear sweep voltammetry, differential pulse voltammetry and chronocoulometry. The binding number and association constant between azithromycin and bovine serum albumin have been obtained.

References

Jul 31, 1998·Journal of Pharmaceutical and Biomedical Analysis·T Turcinov, S Pepeljnjak

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Citations

Mar 10, 2016·Materials Science & Engineering. C, Materials for Biological Applications·Bolu SunWanghong Zhao
May 16, 2012·Colloids and Surfaces. B, Biointerfaces·Shweta J MalodeSharanappa T Nandibewoor
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Jan 31, 2006·Bioelectrochemistry·Sebojka Komorsky-Lovrić
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Mar 11, 2015·Spectrochimica Acta. Part A, Molecular and Biomolecular Spectroscopy·N Rajendiran, J Thulasidhasan
Oct 25, 2011·Luminescence : the Journal of Biological and Chemical Luminescence·Huazhen YeGuonan Chen
Jan 15, 2011·Analytical Sciences : the International Journal of the Japan Society for Analytical Chemistry·Feng GeChaoyin Chen

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