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Studies on IgA and IgA monoclonal proteins derived from a single patient. Evidence for identical light chains and variable regions of the heavy chain

Biochemistry

Dec 30, 1975

D S FairLeroy E Hood

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Abstract

Two immunoglobulins, IgA(K) and IgG(K), were isolated from the serum of a single patient with two monoclonal components (biclonal proteins). After chain separation, the light chains from each molecule were found to be identical by the following criteria: electrophoretic mobilities under...read more

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IgA2
IgG2B
Polyglobin
Hydrogen-Ion Concentration
Immunoglobulin Heavy Chain Subgroup VH-III
Trypure
Avazyme
Peptide Fragments
Immunoglobulin Light Chains
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  • Studies on IgA and IgA monoclonal proteins derived from a single patient. Evidence for identical light chains and variable regions of the heavy chain

    Biochemistry

    Dec 30, 1975

    D S FairLeroy E Hood

    PMID: 1085

    DOI: 10.1021/bi00697a004

    Abstract

    Two immunoglobulins, IgA(K) and IgG(K), were isolated from the serum of a single patient with two monoclonal components (biclonal proteins). After chain separation, the light chains from each molecule were found to be identical by the following criteria: electrophoretic mobilities under...read more

    Mentioned in this Paper

    IgA2
    IgG2B
    Polyglobin
    Hydrogen-Ion Concentration
    Immunoglobulin Heavy Chain Subgroup VH-III

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