PMID: 1200997Sep 1, 1975Paper

Studies on mixed monolayers of phospholipids and fusogenic lipids

The Biochemical Journal
B Maggio, J A Lucy

Abstract

1. The behaviour of mixed monolayers of 14 different lipids with preparations of erythrocyte lipids, purified natural and synthetic phospholipids, cholesterol and galactosylceramide was investigated. 2. The mean areas occupied per molecule in mixed films containing lipids that are fusogenic for hen erythrocytes were compared with those for corresponding films containing lipids that are inactive as fusogens. 3. Fusogenic lipids were found to exhibit interactions, which were not shown by non-fusogenic lipids, in mixed monolayers with several species of phospholipid, particularly those containing a choline head group. 4. Heterogeneity in the hydrophobic chains of phosphatidylcholine, their degree of unsaturation and the presence of cholesterol had little effect on the interaction of phosphatidylcholine with fusogenic lipids. 5. Fusogenic lipids showed little specific interaction with natural or synthetic preparations of phosphatidylethanolamine. 6. The possible significance of these observations in relation to the action of fusogenic lipids on biological membranes is discussed in the light of the asymmetrical distribution of phospholipids in erythrocyte membranes.

Citations

Jun 4, 2011·Chemistry and Physics of Lipids·Franco Vega MercadoNatalia Wilke
Jan 27, 2005·Biochimica Et Biophysica Acta·Graciela A BorioliBruno Maggio
Dec 31, 2011·Chemistry and Physics of Lipids·Gergely MilosevitsJános Szebeni
Jun 11, 2011·Journal of Lipids·Sutapa Mondal Roy, Munna Sarkar
May 3, 2014·Langmuir : the ACS Journal of Surfaces and Colloids·Thabo J MatshayaRaquel V Vico
Apr 1, 1993·Journal of Cellular Biochemistry·K YaoJ C Carlson
Jun 1, 1978·FEBS Letters·B MaggioR Caputto
May 1, 1983·Acta Oto-laryngologica·W J Oosterveld
Nov 27, 2018·Pharmaceutical Development and Technology·Bashar A AlkhalidiAl-Sayed Sallam
Sep 1, 1986·Neurochemical Research·G J Brewer, P D Thomas
Jan 26, 2021·Langmuir : the ACS Journal of Surfaces and Colloids·Martín E VillanuevaRaquel V Vico
Jan 13, 1988·Biochimica Et Biophysica Acta·D S Johnston, D Chapman
Oct 19, 1979·Biochimica Et Biophysica Acta·C P Tilcock, D Fisher
Sep 14, 1978·Biochemical and Biophysical Research Communications·F A CumarR Caputto

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