Sep 17, 1976

Studies on optimising rubella virus haemagglutination-inhibitor tests

Deutsche medizinische Wochenschrift
J LeidelH J Eggers

Abstract

Immuno-electrophoretic and serological studies were undertaken to characterise the non-specific serum inhibitor of rubella haemagglutination. The majority of such inhibitor effects come from the beta(1)-lipoproteins. In addition, small inhibitory effects which were due to alpha(1)-lipoproteins were noted in some sera. The result of the tests is influenced less by removing the inhibitor than by conditions of incubation of the serum-antigen mixture, especially pH. The test is more sensitive if it is not performed at optimal pH for haemagglutination.

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Mentioned in this Paper

Hemagglutination Inhibition Tests
Immunoelectrophoresis
Hemagglutination
LDL-1
Rubella
Phosphoglycerate Dehydrogenase Activity
Antigens
PHGDH wt Allele
Lipoproteins
Rubella virus vaccine

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