PMID: 4895539Jun 1, 1969Paper

Studies on repression of the histidine operon. II. The role of the first enzyme in control of the histidine system

Proceedings of the National Academy of Sciences of the United States of America
J S KovachR Goldberger

Abstract

Recent studies on repression of the enzymes for histidine bio-synthesis in Salmonella typhimurium demonstrated that the kinetic pattern in which the enzymes become repressed is influenced by the state of the feedback-sensitive site of the first enzyme of the pathway (Kovach et al., J. Bacteriol., 97, 1283 (1969)). In the present study we demonstrate that under certain conditions alteration of the feedback-sensitive site of the first enzyme prevents repression of the histidine operon. We conclude that the first enzyme plays a previously unrecognized role in regulation of the histidine system.

References

Jan 1, 1966·Cold Spring Harbor Symposia on Quantitative Biology·J R RothB N Ames
Sep 30, 1968·Biochemical and Biophysical Research Communications·E DudaG Dénes
Jan 1, 1966·Cold Spring Harbor Symposia on Quantitative Biology·A L Cline, R M Bock
Aug 1, 1965·Proceedings of the National Academy of Sciences of the United States of America·G A O'Donovan, J L Ingraham
Apr 1, 1960·Journal of General Microbiology·B N AMESL A HERZENBERG
Sep 1, 1964·Journal of Molecular Biology·S SCHLESINGER, B MAGASANIK

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Citations

Jan 24, 1973·Molecular & General Genetics : MGG·C A Lomax, R A Woods
Aug 1, 1970·Proceedings of the National Academy of Sciences of the United States of America·G W Hatfield, R O Burns
Sep 1, 1971·Proceedings of the National Academy of Sciences of the United States of America·A P Bollon, P T Magee
Oct 1, 1973·Proceedings of the National Academy of Sciences of the United States of America·D H Calhoun, G W Hatfield
Sep 1, 1973·Proceedings of the National Academy of Sciences of the United States of America·F BlasiM M Meyers
Dec 1, 1975·Proceedings of the National Academy of Sciences of the United States of America·J F ScottS W Artz
Sep 1, 1975·Proceedings of the National Academy of Sciences of the United States of America·S W Artz, J R Broach
Aug 9, 2007·Journal of Molecular Evolution·Ethan O PerlsteinStuart L Schreiber
Jan 1, 1974·Molecular & General Genetics : MGG·A AvitabileF Blasi
Jan 1, 1973·Molecular & General Genetics : MGG·E BoyJ C Patte
Apr 1, 1971·Archives of Biochemistry and Biophysics·J E FlatgaardU Henning
May 1, 1972·Archives of Biochemistry and Biophysics·H F KungH Weissbach
Feb 20, 1970·Biochemical and Biophysical Research Communications·R M Bell, D E Koshland
Nov 21, 1973·Nature: New Biology·M LevinthalH E Umbarger
Jan 27, 1971·Nature: New Biology·C A Lomax, R A Woods
Sep 1, 1971·Die Naturwissenschaften·G Gerisch
Aug 1, 1972·Journal of Bacteriology·M A SavinC Slaughter
Jan 1, 1993·Journal of Bacteriology·S Maloy, V Stewart
Dec 1, 1975·Journal of Bacteriology·V M FernándezA O Ballesteros
Mar 1, 1974·Science·R F Goldberger

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