PMID: 5168Feb 1, 1976

Studies on the chemical nature of urinary chemiluminescence

British Journal of Urology
G A Rose

Abstract

Studies on the nature of the chemicals responsible for urinary chemiluminescence have been carried out. Urinary chemiluminescence can be increased slightly by sulphatase, more by glucuronidase but most of all by boiling for 1 hour at pH 1. It is suggested that most of the chemicals responsible for urinary chemiluminescence are bound as non-chemiluminescent precursors to sulphate, glucuronic acid and in other ways. Both the chemiluminescent material and the inactive precursors are freely ultrafiltrable with molecular weights below 500. A survey of various chemicals has revealed considerable chemiluminescence in certain metabolites of naphthylamines and known to cause bladder cancer but little or no chemoluminescence in the tryptophane metabolites that have been thought to cause bladder cancer.

References

Jul 26, 1974·Nature·I A Evans, M A Osman
Mar 1, 1972·Clinica Chimica Acta; International Journal of Clinical Chemistry·G A Rose
Dec 1, 1969·British Journal of Urology·J U SchlegelG N Shultz
Jan 21, 1971·The New England Journal of Medicine·P ColeG H Friedell
Mar 1, 1969·The Journal of Urology·J U SchlegelG A Duke
Jan 1, 1969·Urologia Internationalis·C A Veys
Dec 27, 1947·Nature·W ANDERSON

Citations

Jan 1, 1992·Free Radical Biology & Medicine·E A LissiL A Videla
Dec 1, 1984·British Journal of Urology·C P Chilton, G A Rose
Feb 1, 1980·The Journal of Hygiene·H G Hajenian, M Butler
Oct 5, 1989·Biotechnology and Bioengineering·R G ProtheroeA Matchett

Related Concepts

Chromatography
Canis familiaris
Exo-beta-D-Glucuronidase
Eryhem
Hydrogen-Ion Concentration
Hydrolysis
Phosphorescent Measurements
Sulfatases
Ultrafiltration
Urine

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