PMID: 38299Jan 1, 1978

Studies on the control of pineal indole synthesis: cyclic nucleotides, adenylate cyclase and phosphodiesterase

Journal of Neural Transmission. Supplementum
M A Oleshansky, N H Neff

Abstract

An overview of the biochemical events that occur when postsynaptic pineal beta-adrenergic receptors are stimulated is presented. Emphasis is placed on the importance of the adenylate cyclase system for the induction of N-acetyltransferase (NAT). Super- and subsensitive responses of NAT to receptor agonists are related to cAMP concentration, adenylate cyclase and phosphodiesterase activities and receptor binding sites.

Related Concepts

Acetyltransferase
Adenylate Cyclase
Adrenergic beta-Agonists
Circadian Rhythms
Enzyme Induction
Nucleotides, Cyclic
Pineal Gland
Norepinephrine Receptors
Beta-adrenergic receptor
Protein Biosynthesis

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