PMID: 38299Jan 1, 1978

Studies on the control of pineal indole synthesis: cyclic nucleotides, adenylate cyclase and phosphodiesterase

Journal of Neural Transmission. Supplementum
M A Oleshansky, N H Neff


An overview of the biochemical events that occur when postsynaptic pineal beta-adrenergic receptors are stimulated is presented. Emphasis is placed on the importance of the adenylate cyclase system for the induction of N-acetyltransferase (NAT). Super- and subsensitive responses of NAT to receptor agonists are related to cAMP concentration, adenylate cyclase and phosphodiesterase activities and receptor binding sites.

Related Concepts

Adenylate Cyclase
Adrenergic beta-Agonists
Circadian Rhythms
Enzyme Induction
Nucleotides, Cyclic
Pineal Gland
Norepinephrine Receptors
Beta-adrenergic receptor
Protein Biosynthesis

Related Feeds

Adrenergic Receptors: Trafficking

Adrenergic receptor trafficking is an active physiological process where adrenergic receptors are relocated from one region of the cell to another or from one type of cell to another. Discover the latest research on adrenergic receptor trafficking here.