PMID: 7370921Apr 1, 1980Paper

Studies on the difference of background mucosa among single advanced carcinoma and benign diseases of the large intestine, and familial polyposis coli

Cancer
T OoharaH Tohma

Abstract

The entire lengths of fixed specimens from 17 single advanced carcinomas of the colon (Cancer Group), four benign lesions (Benign Group), and four familial polyposis coli (Polyposis Group) were step-sectioned. It was found that the tubules of the basal cells were densely packed with rather a small number of goblet cells in the cancer and benign lesion specimens, but clear and loose with completely differentiated goblet cells in the polyposis coli specimens. Microscopic adenomas that were macroscopically unrecognizable and only microscopically detectable were found in 16 lesions in the Cancer Group, one lesion in the Benign Group, and in numerous lesions in the Polyposis Group. All of them developed from the basal cells. These findings indicate that the colonic mucosa of patients in the Cancer and Benign Groups is similar, but differs from that of the Polyposisis Group, and that microscopic adenomas are not uncommon in the Non-Polyposis Groups (Cancer and Benign Groups), findings which were not previously known.

References

Jan 1, 1977·Cancer·P HaghighiN Mostafavi
May 1, 1975·The British Journal of Surgery·B Leppard, H J Bussey
Sep 1, 1974·Cancer·C M Fenoglio, N Lane
Nov 1, 1970·Cancer·C G Bremner, L V Ackerman
Nov 1, 1968·Journal of Clinical Pathology·J F Arthur
Jan 1, 1959·Diseases of the Colon and Rectum·E B HELWIG
Sep 6, 1962·The New England Journal of Medicine·B CASTLEMAN, H I KRICKSTEIN
Feb 3, 1962·JAMA : the Journal of the American Medical Association·J S SPRATT, L V ACKERMAN

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Citations

Jan 1, 1992·Journal of Cellular Biochemistry. Supplement·T P PretlowT A Stellato
Feb 1, 1990·Diseases of the Colon and Rectum·S KuramotoT Oohara
Jun 1, 1983·Diseases of the Colon and Rectum·S R Hamilton
Jan 1, 1987·Diseases of the Colon and Rectum·S KuramotoY Kondo
Jul 1, 1981·Diseases of the Colon and Rectum·T OoharaH Tohma
Jul 13, 1981·Life Sciences·J Heaney-Kieras, F J Kieras
Nov 1, 1984·Clinical Radiology·B C Morson
Mar 6, 2010·Journal of the American Chemical Society·Kheireddine El-BoubbouXuefei Huang
Apr 1, 1989·Japanese Journal of Cancer Research : Gann·T Muto
Jul 1, 1997·Gastrointestinal Endoscopy·T YokotaS Yoshida
Feb 15, 1988·Cancer·S Kuramoto, T Oohara
Jan 1, 1986·Virchows Archiv. B, Cell Pathology Including Molecular Pathology·P RomagnoliP Bechi
Mar 30, 1999·The Proceedings of the Nutrition Society·J J Belch, A Muir

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