PMID: 6984166Nov 1, 1982Paper

Studies on the host-parasite relationship of Schistosoma japonicum in normal and immunosuppressed mice

Parasite Immunology
N A MoloneyP Hinchcliffe

Abstract

Infections of Schistosoma japonicum were studied in mice which were immunosuppressed either by thymectomy and administration of antithymocyte serum or by treatment with hydrocortisone acetate. The relation of S. japonicum with the immunosuppressed host differed with that reported for Schistosoma mansoni. The pathogenesis of the S. japonicum infection in the immunosuppressed host was less severe than that caused by S. mansoni, with respect to survival of, and hepatocellular damage to, the host. In contrast with S. mansoni, S. japonicum did not have a reduced fecundity in immunosuppressed mice and there was no significant reduction in the numbers of faecal eggs excreted by these hosts.

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Citations

Jan 1, 1986·Transactions of the Royal Society of Tropical Medicine and Hygiene·M J DoenhoffS Lucas
Aug 23, 2000·Immunology Today·A W CheeverT A Wynn
Apr 17, 2003·Trends in Immunology·Michael J Doenhoff
Oct 1, 1983·Parasitology·N A Moloney, G Webbe
Dec 18, 2003·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Stan HoustonKen Warren
May 1, 1993·Parasite Immunology·A M AgnewM J Doenhoff
Jul 1, 1985·Parasite Immunology·A W CheeverF von Lichtenberg
Sep 7, 2005·Molecular and Biochemical Parasitology·Colin M FitzsimmonsDavid W Dunne
Jan 1, 1984·European Journal of Clinical Pharmacology·N OdumI C Bygbjerg
Jul 7, 2020·FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology·Wen-Jun ChengHong Jiang
Mar 19, 2020·Parasitology Research·Wenling HuangHuifen Dong

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