PMID: 2506897Feb 1, 1989Paper

Studies on the immunoregulative action of polysaccharides isolated from hyphal bodies of Lentinnus edodes (PHL) on hypoimmunity in mice

Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica
X Y ZengF He

Abstract

PHL possesses significant antagonist action for immunodepression in mice induced by different immunodepressors. It can reverse the hypomacrophage function and the reduction in percentage of T-lymphoid cell induced by hydrocortisone (50 or 80 mg/kg, sc), reverse the reduction of phagocytosis of reticuloendothelial system (RES) induced by hydroprednisone acetate (20 and 40 mg/kg, ip), restore the cyclophosphamide-suppressed delayed anaphylaxis reaction in mice (40 and 80 mg/kg, ip). In vitro PHL at a dose of 1 and 10 micrograms/ml accelerated lymphocyte mitosis induced by conA and PHA.

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Anaphylaxis

Anaphylaxis is a serious allergic reaction that is rapid in onset and may cause death.