Jan 1, 1976

Studies on the inhibition of thermolysin

Experientia. Supplementum
J FederB S Wildi

Abstract

Thei nhibition of the thermolysin catalyzed hydrolysis of FA-Gly-Leu-NH2 and FA-Gly-Phe-NH2 has been reported. The results suggest a model for substrate and inhibitor binding involving the hydrophobic specificity pocket, Arg-203 and Glu-143.

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Mentioned in this Paper

Oligopeptides
Metabolic Inhibition
3-(2-furylacryloyl)glycine
Endorphenyl
Thermolysin
Leucine
Hydrogen-Ion Concentration

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