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Studies on the mechanism of depletion of striatal dopamine by alpha-methyl-m-tyrosine

The Journal of Pharmacology and Experimental Therapeutics

Dec 1, 1975

N J UretskyA V Lorenzo

PMID: 490

Abstract

These experiments were designed to study the mechanism of depletion of dopamine (DA) in the striatum produced by alpha-methyl-m-tyrosine (alpha-MMT). alpha-Methyl-m-tyramine (alpha-MMTA), the metabolite of alpha-MMT, appears to be the active DA-depleting agent, since the administration ...read more

Mentioned in this Paper

Homovanillic Acid
TH gene
Dopamine Measurement
Homovanillic Acid Measurement
Metabolic Inhibition
Metabolic Process, Cellular
Metabolism
Metabolic Aspects
Methyltyrosines
Ro 4-4602
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Studies on the mechanism of depletion of striatal dopamine by alpha-methyl-m-tyrosine

The Journal of Pharmacology and Experimental Therapeutics

Dec 1, 1975

N J UretskyA V Lorenzo

PMID: 490

DOI:

Abstract

These experiments were designed to study the mechanism of depletion of dopamine (DA) in the striatum produced by alpha-methyl-m-tyrosine (alpha-MMT). alpha-Methyl-m-tyramine (alpha-MMTA), the metabolite of alpha-MMT, appears to be the active DA-depleting agent, since the administration ...read more

Mentioned in this Paper

Homovanillic Acid
TH gene
Dopamine Measurement
Homovanillic Acid Measurement
Metabolic Inhibition
Metabolic Process, Cellular
Metabolism
Metabolic Aspects
Methyltyrosines
Ro 4-4602

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