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Studies on the mechanism of depletion of striatal dopamine by alpha-methyl-m-tyrosine

The Journal of Pharmacology and Experimental Therapeutics

Dec 1, 1975

N J UretskyA V Lorenzo

PMID: 490

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Abstract

These experiments were designed to study the mechanism of depletion of dopamine (DA) in the striatum produced by alpha-methyl-m-tyrosine (alpha-MMT). alpha-Methyl-m-tyramine (alpha-MMTA), the metabolite of alpha-MMT, appears to be the active DA-depleting agent, since the administration ...read more

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Congenital Abnormal Synostosis
Methyltyrosines
Homovanillic Acid Measurement
3,4-Dihydroxyphenylacetic Acid
NSD-1055
Decarboxylase inhibitor
TH gene
Paredrine
3,4-Dihydroxyphenylacetic Acid, Monosodium Salt
Metabolic Inhibition
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  • Studies on the mechanism of depletion of striatal dopamine by alpha-methyl-m-tyrosine

    The Journal of Pharmacology and Experimental Therapeutics

    Dec 1, 1975

    N J UretskyA V Lorenzo

    PMID: 490

    DOI:

    Abstract

    These experiments were designed to study the mechanism of depletion of dopamine (DA) in the striatum produced by alpha-methyl-m-tyrosine (alpha-MMT). alpha-Methyl-m-tyramine (alpha-MMTA), the metabolite of alpha-MMT, appears to be the active DA-depleting agent, since the administration ...read more

    Mentioned in this Paper

    Congenital Abnormal Synostosis
    Methyltyrosines
    Homovanillic Acid Measurement
    3,4-Dihydroxyphenylacetic Acid
    NSD-1055

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