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Studies with the folate binding protein in chronic granulocytic leukaemia cells. I. Synthesis and release of binder by cells in short-term culture

British Journal of Haematology

Dec 1, 1976

M da Costa, S P Rothenberg

Abstract

Chronic granulocytic leukaemia (CGL) cells which contained a high concentration of unsaturated folate binding protein were incubated in suspension culture for a period of 5 h. Cell samples were periodically assayed for binder and these demonstrated active synthesis which was inhibited b...read more

Mentioned in this Paper

Plasma Protein Binding Capacity
Leukemia, Monocytic, Chronic
Chromatography, Agarose
Folate
FOLR1
Myeloid Leukemia, Chronic
Myeloid Leukemia
Carrier Proteins
Ac-De
Folic Acid, Sodium Salt
Paper Details
References
  • References3
  • Citations2
1
  • References3
  • Citations2
1

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Studies with the folate binding protein in chronic granulocytic leukaemia cells. I. Synthesis and release of binder by cells in short-term culture

British Journal of Haematology

Dec 1, 1976

M da Costa, S P Rothenberg

PMID: 1068709

DOI: 10.1111/j.1365-2141.1976.tb03604.x

Abstract

Chronic granulocytic leukaemia (CGL) cells which contained a high concentration of unsaturated folate binding protein were incubated in suspension culture for a period of 5 h. Cell samples were periodically assayed for binder and these demonstrated active synthesis which was inhibited b...read more

Mentioned in this Paper

Plasma Protein Binding Capacity
Leukemia, Monocytic, Chronic
Chromatography, Agarose
Folate
FOLR1
Myeloid Leukemia, Chronic
Myeloid Leukemia
Carrier Proteins
Ac-De
Folic Acid, Sodium Salt

Similar Papers Found In These Feeds

Myeloid Stem Cells & CML

Chronic Myeloid Leukemia (CML) is a stem cell cancer that arises due to the fusion and constitutive expression of BCR-ABL1 in hematopoietic stem cells, which give rise to both myeloid and lymphoid cell lineages. CML is characterized by increased and unregulated proliferation of myeloid cells. Here is the latest research.

Chronic Myelogenous Leukemia

Chronic myelogenous leukemia (cml) is a clonal hematopoietic stem cell disorder characterized by the translocation and resultant production of the constitutively activated bcr-abl tyrosine kinase. Here is the latest research on this disease.

Related Papers

British Journal of Haematology

The synthesis of folate-binding protein in lymphocytes during transformation

British Journal of HaematologyDecember 1, 1980
M da Costa, M Sharon
Paper Details
References
  • References3
  • Citations2
1
  • References3
  • Citations2
1
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