Study and formation of vesicle systems with low polydispersity index by ultrasound method

Chemistry and Physics of Lipids
J Pereira-LachataigneraisO López

Abstract

The formation of liposomes with low polydispersity index by application of ultrasounds was investigated considering methodology specifications such as sonication time and sonication power. Phosphatidylcholine (PC) liposomes were formed by the evaporation-hydration method. The vesicles were sonicated using several sonication conditions. The liposomes were then characterized by dynamic light scattering (DLS) and freeze-fracture electron microscopy (FFEM). Correlation functions from DLS were treated by cumulants method and GENDIST to obtain the mean radius and polydispersity index. These calculations allowed to fix an optimal sonication time (3000 s) and a useful interval of ultrasound power between 39 and 91 W. DLS and FFEM results confirmed that vesicle size, lamellarity and the polydispersity index decreased with the increase of sonication power. Thus, we propose a systematic method to form liposomes in which the physical characteristics of the vesicles may be controlled as a function of sonication time and power.

References

Dec 1, 1991·Chemistry and Physics of Lipids·R AlmogC Samsonoff
Dec 1, 1995·Trends in Biotechnology·G Gregoriadis
Feb 1, 1997·European Journal of Biochemistry·J CladeraM Duñach
Nov 25, 2000·Biochimica Et Biophysica Acta·M OllivonM Paternostre
Feb 15, 2001·Proceedings of the National Academy of Sciences of the United States of America·H T JungE W Kaler
Jul 1, 1997·Ultrasonics Sonochemistry·P KruusR Otson
Jan 1, 1996·Advances in Space Research : the Official Journal of the Committee on Space Research (COSPAR)·D E Claassen, B S Spooner
May 26, 2005·European Journal of Pharmaceutics and Biopharmaceutics : Official Journal of Arbeitsgemeinschaft Für Pharmazeutische Verfahrenstechnik E.V·Laura Rabinovich-GuilattPierre Chaminade

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Citations

Sep 13, 2011·Biomacromolecules·Raquel SilvaArtur Cavaco-Paulo
Apr 7, 2011·Langmuir : the ACS Journal of Surfaces and Colloids·Omar Mertins, Rumiana Dimova
May 6, 2014·European Journal of Pharmaceutical Sciences : Official Journal of the European Federation for Pharmaceutical Sciences·Sami AhmedMohamed Ahmed El-Nabarawi
Jul 9, 2008·Journal of Microencapsulation·Maha NasrA A Elshamy
Jun 12, 2009·Journal of Liposome Research·R RamírezL Coderch
Jun 25, 2014·Journal of Liposome Research·Shirin TavakoliSoliman Mohammadi Samani
Apr 15, 2014·Journal of Liposome Research·Gülengül DumanAlpay Taralp
Dec 24, 2013·Drug Delivery·Mohammed Shafik El-RidyMarwa Hasanin Asfour
Oct 28, 2015·FEBS Open Bio·Antonio FilippiEnrico Braidot
Nov 23, 2015·Colloids and Surfaces. B, Biointerfaces·Marco PainiPeter Valtchev
Dec 3, 2014·European Journal of Pharmaceutical Sciences : Official Journal of the European Federation for Pharmaceutical Sciences·Neeraj Kumar, Shishu
Apr 29, 2009·Chemistry and Physics of Lipids·Tsuyoshi YamaguchiShinobu Koda
May 20, 2008·International Journal of Pharmaceutics·Yimei JiaAbdelwahab Omri
May 10, 2008·Ultrasonics Sonochemistry·Raquel SilvaArtur Cavaco-Paulo
Apr 5, 2008·Journal of Microscopy·L Barbosa-BarrosO López
Nov 9, 2011·Biochimica Et Biophysica Acta·Sofía AngelettiMaría A Perillo
May 6, 2014·BioMed Research International·Bahareh SabetiHamid Akbari Javar
Apr 2, 2016·Drug Development and Industrial Pharmacy·Ahmed A H AbdellatifHesham M Tawfeek
Dec 14, 2011·Langmuir : the ACS Journal of Surfaces and Colloids·Kadla R RosholmOle G Mouritsen
Jun 7, 2013·Langmuir : the ACS Journal of Surfaces and Colloids·Chih-Wei WangMatthew G Moffitt
Sep 9, 2016·AAPS PharmSciTech·Muhammad Imran KhanLeena Peltonen
Sep 8, 2016·European Journal of Pharmaceutical Sciences : Official Journal of the European Federation for Pharmaceutical Sciences·Muhammad Imran KhanLeena Peltonen
Aug 31, 2016·Pharmaceutical Development and Technology·Babita Kumari, Karthikeyan Kesavan
Feb 7, 2017·Soft Matter·Roberto Diego OrtusoKaori Sugihara
Mar 13, 2018·Advanced Healthcare Materials·Zhanfeng LiXuejun Cui
Jun 26, 2018·Drug Development and Industrial Pharmacy·Ahmed A H Abdellatif, Hesham M Tawfeek
Dec 12, 2018·Journal of Liposome Research·Mohamed S El-RidyMenna Ahmed El-Gamil
Feb 5, 2019·Journal of Food Science·Zhongqi SunYanyun Zhao
Apr 16, 2020·Journal of Microencapsulation·Atinderpal KaurShweta Dang
Aug 21, 2015·Journal of Materials Chemistry. B, Materials for Biology and Medicine·R ZappacostaA Fontana
Apr 4, 2021·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Johana AndradeAmparo Chiralt
Aug 30, 2008·The Journal of Physical Chemistry. B·Alberto Rodríguez-PulidoElena Junquera
Oct 31, 2013·Langmuir : the ACS Journal of Surfaces and Colloids·Omar Mertins, Rumiana Dimova
Jun 28, 2019·Langmuir : the ACS Journal of Surfaces and Colloids·Maria TsemperouliKaori Sugihara
Jan 29, 2008·The Journal of Physical Chemistry. B·Alberto Rodríguez-PulidoElena Junquera
Feb 27, 2007·Langmuir : the ACS Journal of Surfaces and Colloids·Avi SchroederYechezkel Barenholz

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