[Study concerning the effects of exercise on the frequency of ventricular premature contraction. A new classification and its clinical implications].

Nihon Ika Daigaku zasshi
K Iida

Abstract

The effects of exercise on the frequency of ventricular premature contraction (VPC) and the clinical implications thereof were studied in 95 patients. Patients with ischemic heart disease and severe congestive heart failure were excluded from the study. The patients were divided into 7 groups according to changes in the frequency of VPC during and after exercise. Clinical background, exercise parameters and the efficacy of antiarrhythmic drugs were compared among these 7 groups. Plasma catecholamine concentration was measured in 34 patients, with a group of 12 healthy subjects serving as controls. An increase in the frequency of VPC both during and after exercise was observed in 16 patients (Group II). In comparison with the other groups, this group was older, and exhibited a higher incidence of underlying heart disease, lower tolerance to exercise and more serious ventricular arrhythmias. Beta-blockers were the most effective treatment for this group. However, plasma catecholamine concentration was not significantly higher in this group than it was in the other groups or the healthy subjects. A decrease in the frequency of VPC during exercise and an increase after exercise was observed in 25 patients (Group DI). This group als...Continue Reading

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