Study of 71 cases of visceral leishmaniasis diagnosed at the Mustapha University Hospital (Algiers) from 1998 to 2009

Médecine et maladies infectieuses
H ZaitB Hamrioui

Abstract

The authors retrospectively studied the epidemiological, clinical, diagnostic and therapeutic aspects of 71 cases of visceral leishmaniasis from 1998 to 2009. The diagnosis was made by finding Leishmania amastigotes in bone marrows smears and/or by serology. Most cases occur in winter (35.2%) and in spring (36.6%). The source areas are endemic ones located in the north of Algeria (74.6%) and more rarely arid or semi-arid climate areas (8.4%). 88.7% of patients are children. The sex ratio is 1.53. The clinical characteristics are: fever (77.4%), paleness (43.6%); splenomegaly (83%), hepatomegaly (57.7%). The biological anomalies are: anemia (56.3%), thrombocytopenia (33.8%), and leucopenia (28.1%). N-methylglucamine (Glucantime(®)) was most often prescribed (70.4%). Four deaths (5.6%) were recorded. Visceral leishmaniasis remains a pediatric affection but does not spare adults.

References

Nov 1, 1996·Transactions of the Royal Society of Tropical Medicine and Hygiene·Z HarratJ P Dedet

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Citations

Jun 21, 2014·PloS One·Amel AdelMarleen Boelaert
Mar 22, 2018·PLoS Neglected Tropical Diseases·Naouel EddaikraDenis Sereno
May 8, 2020·Interdisciplinary Perspectives on Infectious Diseases·Fatima Zahra TalbiAbdelhakim El Ouali Lalami

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