Study of association of severity of sleep disordered breathing and functional outcome in stroke patients

Sleep Medicine
Rohit KumarRajesh Manocha

Abstract

Sleep disordered breathing (SDB) is a prevalent yet underrecognized condition that may have major adverse consequences for those affected by it. We performed a prospective observational study to seek a correlation of severity of SDB with the severity of stroke and its functional outcome. Patients with history of recent-onset stroke were recruited and underwent overnight polysomnography (PSG) after the acute phase of the stroke was over; for defining hypopneas, 3% and 4% desaturation limits were used, and the apnea-hypopnea index was respectively calculated as AHI3%and AHI4%. Stroke severity was graded using the Scandinavian Stroke Scale. Functional disability and neurological impairment was evaluated six weeks after the PSG using the Barthel Index (<80 = functional dependence; ≥80 = functional independence) and modified Rankins Scale (>2 = poor outcome; ≤2 = good outcome). A total of 50 patients were enrolled, 30 (60%) with ischemic stroke and 20 (40%) with hemorrhagic strokes. Of the patients, 39 (78%) had an AHI4%of >5/h, 23 (46%) had an AHI4%of >15/h, and 9 (18%) had an AHI4%of >30/h. Multivariate analysis showed that body mass index (odds ratio [OR] = 1.26; 95% confidence interval [CI] = 1.04-1.54, p = 0.019) and Scandinavi...Continue Reading

Citations

Jun 9, 2020·Neurorehabilitation and Neural Repair·Melanie K FlemingHeidi Johansen-Berg
Jul 11, 2019·Sleep & Breathing = Schlaf & Atmung·Zachary McKeeDennis H Auckley
Apr 23, 2020·The European Respiratory Journal·Claudio L A BassettiVasileios Papavasileiou
Apr 22, 2020·European Journal of Neurology : the Official Journal of the European Federation of Neurological Societies·C L A BassettiV Papavasileiou
Dec 19, 2019·Current Sleep Medicine Reports·H Lee LauAlberto R Ramos
Aug 21, 2021·Artificial Intelligence in Medicine·Andrea BernardiniNicola Saccomanno

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