Study of cardiovascular disease biomarkers among tobacco consumers, part 2: biomarkers of biological effect

Inhalation Toxicology
Brian K NordskogMichael F Borgerding

Abstract

An age-stratified, cross-sectional study was conducted in the US among healthy adult male cigarette smokers, moist snuff consumers, and non-tobacco consumers to evaluate cardiovascular biomarkers of biological effect (BoBE). Physiological assessments included flow-mediated dilation, ankle-brachial index, carotid intima-media thickness and expired carbon monoxide. Approximately one-half of the measured serum BoBE showed statistically significant differences; IL-12(p70), sICAM-1 and IL-8 were the BoBE that best differentiated among the three groups. A significant difference in ABI was observed between the cigarette smokers and non-tobacco consumer groups. Significant group and age effect differences in select biomarkers were identified.

References

Nov 21, 1992·BMJ : British Medical Journal·F HuhtasaariP O Wester
Jul 1, 1991·Journal of Internal Medicine·M EliassonE Hägg
Dec 1, 1990·Proceedings of the National Academy of Sciences of the United States of America·J D MorrowL J Roberts
Mar 25, 1989·BMJ : British Medical Journal·W Y CraigJ E Haddow
Oct 13, 1989·Biochimica Et Biophysica Acta·S E BarrowC T Dollery
Aug 1, 1989·American Journal of Public Health·L A Tucker
Mar 1, 1994·American Journal of Public Health·G BolinderU de Faire
Jul 1, 1996·Circulation·M ReillyG A FitzGerald
Jul 1, 1997·The Journal of Laboratory and Clinical Medicine·B JilmaO F Wagner
Apr 9, 1998·Prostaglandins·J RokachG A FitzGerald
Jul 21, 1998·Journal of the American College of Cardiology·S ThorneJ E Deanfield
Sep 22, 1998·Arteriosclerosis, Thrombosis, and Vascular Biology·P M Mannucci
Jan 15, 2000·Arteriosclerosis, Thrombosis, and Vascular Biology·J W YarnellG D Lowe
Jan 15, 2002·Journal of the American College of Cardiology·Thomas NeunteuflThomas Stefenelli
Mar 1, 2002·Diabetic Medicine : a Journal of the British Diabetic Association·N TakeuchiN Hotta
Mar 6, 2003·Vascular Pharmacology·Moniek P M de Maat, Cornelis Kluft
Feb 12, 2004·Journal of Internal Medicine·M Rohani, S Agewall
Nov 4, 2004·Vascular Medicine·Christos M PapamichaelMyron E Mavrikakis
Nov 27, 2004·Circulation Journal : Official Journal of the Japanese Circulation Society·Ali Metin EsenCevat Kirma
Dec 23, 2004·Epidemiology·Maria-Pia HergensGöran Pershagen
Oct 31, 2006·International Journal of Cardiology·Kalliopi KaratziJohn Lekakis
Nov 30, 2006·Scandinavian Journal of Public Health·Margareta NorbergLars Weinehall
Sep 6, 2007·Hypertension Research : Official Journal of the Japanese Society of Hypertension·Kunio YufuHironobu Yoshimatsu
Feb 22, 2008·Atherosclerosis·Yamini S LevitzkyEmelia J Benjamin
Dec 2, 2008·Circulation Journal : Official Journal of the Japanese Circulation Society·Kunio YufuHironobu Yoshimatsu
Dec 17, 2008·Cardiovascular & Hematological Disorders Drug Targets·René HaverslagImo E Hoefer
Jan 30, 2009·Basic & Clinical Pharmacology & Toxicology·Gioacchino CalapaiAlfredo Nunziata
Feb 26, 2009·Tobacco Control·Mitchell ZellerUNKNOWN Strategic Dialogue on Tobacco Harm Reduction Group
Mar 12, 2009·Inflammation & Allergy Drug Targets·Katrina GeeAshok Kumar
Mar 21, 2009·American Journal of Hypertension·Gerasimos SiasosChristodoulos Stefanadis
Jul 21, 2009·Cardiovascular Research·Stavros ApostolakisDemetrios A Spandidos
Aug 14, 2009·Clinical Chemistry and Laboratory Medicine : CCLM·Frazer J LoweMichael McEwan
Oct 27, 2009·Inhalation Toxicology·Gioacchino CalapaiAlfredo Nunziata
Nov 21, 2009·Circulation Journal : Official Journal of the Japanese Circulation Society·Osamu YoshidaToyoaki Murohara

❮ Previous
Next ❯

Citations

Nov 4, 2015·Biomarkers : Biochemical Indicators of Exposure, Response, and Susceptibility to Chemicals·Michael W OgdenMitchell F Stiles
Dec 2, 2015·Scientific Reports·Stefan EnrothUlf Gyllensten
Jan 4, 2018·Biomarkers : Biochemical Indicators of Exposure, Response, and Susceptibility to Chemicals·Michael John PeckRolf Weitkunat
Dec 19, 2017·Nicotine & Tobacco Research : Official Journal of the Society for Research on Nicotine and Tobacco·Cindy M ChangDorothy K Hatsukami
Oct 27, 2015·Clinical Chemistry and Laboratory Medicine : CCLM·G L PrasadEvan O Gregg
Sep 29, 2019·Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology·Patrudu MakenaG L Prasad

❮ Previous
Next ❯

Methods Mentioned

BETA
MDS
PCA

Clinical Trials Mentioned

NCT01692353

Related Concepts

Related Feeds

Biomarkers for Cardiovascular Risk Assessment

Sensitive and accurate biomarkers used in cardiovascular risk prediction can potentially be used to manage the risk of cardiovascular disease. Discover the latest research on Biomarkers for Cardiovascular Risk Assessment here. Discover the latest research on Biomarkers for Cardiovascular Risk Assessment here.