Study of hypothalamic metabolism in cluster headache by proton MR spectroscopy

Neurology
R LodiB Barbiroli

Abstract

The authors used 1H-MRS to investigate hypothalamic metabolism in 26 patients with cluster headache (CH) and 12 healthy subjects. Hypothalamic N-acetylaspartate/creatine was reduced in patients with CH vs controls (p < 0.01). Dividing the patients into episodic CH outside- and in-cluster periods and chronic CH, the hypothalamic N-acetylaspartate/creatine in all three subgroups of patients was reduced. The reduction of the neuronal marker N-acetylaspartate is consistent with hypothalamic neuronal dysfunction in patients with CH.

Citations

Jul 17, 2008·Neurological Sciences : Official Journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology·Alberto Proietti CecchiniMassimo Leone
Jul 17, 2008·Neurological Sciences : Official Journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology·Angelo FranziniGiovanni Broggi
Jun 1, 2012·Neurological Sciences : Official Journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology·Massimo LeoneGennaro Bussone
Mar 21, 2007·Current Pain and Headache Reports·Alexandre F M DaSilvaDavid Borsook
May 14, 2008·Current Pain and Headache Reports·Manjit Matharu, Arne May
Apr 29, 2010·Current Pain and Headache Reports·Manjit S Matharu, Ludvic Zrinzo
Dec 4, 2010·Current Pain and Headache Reports·Dagny HolleMark Obermann
Mar 12, 2008·The Neurologist·Rukmini Menon, Cheryl D Bushnell
Aug 2, 2007·Cephalalgia : an International Journal of Headache·T SprengerT R Tölle
Jun 13, 2008·Cephalalgia : an International Journal of Headache·M LeoneG Bussone
Jul 16, 2008·Cephalalgia : an International Journal of Headache·A PerrottaG Nappi
Mar 29, 2014·Current Pain and Headache Reports·Steffen NaegelMark Obermann
Oct 4, 2014·The Journal of Headache and Pain·Rongfei WangShengyuan Yu
Dec 3, 2013·Rinshō shinkeigaku = Clinical neurology·Tomokazu Shimazu
Aug 26, 2011·Expert Review of Neurotherapeutics·Dagny Holle, Mark Obermann
Mar 8, 2011·Expert Review of Neurotherapeutics·Leslie Kelman
Mar 17, 2010·Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia·Till Sprenger, Peter J Goadsby
Jul 18, 2009·Lancet Neurology·Massimo Leone, Gennaro Bussone
Nov 26, 2011·The Journal of Headache and Pain·Elisa IacovelliFederico Bianco
Jul 20, 2007·Headache·Roberto VetrugnoPasquale Montagna
May 21, 2013·Cephalalgia : an International Journal of Headache·Jeppe L PedersenRigmor H Jensen
Mar 29, 2014·Cephalalgia : an International Journal of Headache·Kun-Hsien ChouShuu-Jiun Wang
Jul 6, 2017·Cephalalgia : an International Journal of Headache·Fu-Chi YangShuu-Jiun Wang
Dec 24, 2010·Therapeutic Advances in Neurological Disorders·Massimo LeoneGennaro Bussone
Sep 25, 2017·Clinical Autonomic Research : Official Journal of the Clinical Autonomic Research Society·Mads C J Barloese
Mar 2, 2018·Nature Reviews. Disease Primers·Arne MayShuu-Jiun Wang
Aug 31, 2019·Cephalalgia : an International Journal of Headache·Arne May, Rami Burstein
Jun 1, 2018·Case Reports in Neurological Medicine·Costantini AntonioTrevi Erika
Aug 19, 2018·Journal of Neurology·Srdjan Ljubisavljevic, Jasna Zidverc Trajkovic
May 19, 2021·Neurology India·Steffen Naegel, Mark Obermann

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.