Nov 1, 1975

Study of measles virus (strain L-16) in J-96 cell culture by electron microscopy and immunofluorescence

Voprosy virusologii
L V Dorofeeva, N N Ianova

Abstract

The vaccine L-16 strain of measles virus was studied in a continuous line of J-96 cells (clone L-41) by the electron microscope and fluorescent antibody techniques. Cytological studies revealed a direct correlation between the intensity of symplast formation and the infective virus dose. The fluorescent antibody technique established cytoplasmic localization of the specific virus antigen. The results of electron microscope examinations of ultrathin sections of J-97 culture revealed in the cell cytoplasm and intercellular space some structures morphologically similar to virus-like particles previously described.

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Mentioned in this Paper

Establishment and Maintenance of Localization
Immunofluorescence Assay
Measles virus
Extracellular Space
Cell Culture Techniques
Symplast
Measles virus preparation
Electron Microscopy, Diagnostic
Cytoplasmic
Electron Microscopy

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