PMID: 7336686Sep 1, 1981Paper

Study of regulation of orthomyxovirus virus-specific polypeptides using the ts-mutant of fowl plague virus having a transcription abnormality as a model

Voprosy virusologii
S G Markushin, Iu Z Gendon

Abstract

The synthesis of virus-specific polypeptides in cells infected with a ts-mutant of fowl plague virus with disturbed process of secondary transcription was studied. Synthesis of all virus-specific proteins was shown to occur under conditions providing for synthesis of polyA+ cRNA at the stage of primary transcription but with disturbance of the secondary transcription and blocking of polyA- cRNA and vRNA synthesis. No time regulation of virus-specific polypeptide synthesis was in effect.

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