Study of the diversity and short-chain fatty acids production by the bacterial community in overweight and obese Mexican children

European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology
S MurugesanJ García-Mena

Abstract

Obesity and overweight are health problems of multifactorial etiology, which may include changes in the microbiome. In Mexico, more than 30 % of the child population between 5 and 11 years of age suffer from being overweight or are obese, which makes it a public health issue in progress. The purpose of this work was to measure the short-chain fatty acid concentration by high-performance liquid chromatography (HPLC), and to characterize the bacterial diversity by ion torrent semiconductor sequencing, of 16S rDNA libraries prepared from stools collected from a sample of well-characterized Mexican children for normal weight, overweight, and obese conditions by anthropometric and biochemical criteria. We found that triglyceride levels are increased in overweight and obese children, who presented altered propionic and butyric acid concentrations in feces. In addition, although the colon microbiota did not show a clear bacterial dysbiosis among the three conditions, the abundance of some particular bacteria was changed with respect to normal controls. We conclude from our results that the imbalance in the abundance of at least nine different bacteria as well as altered short-chain fatty acid concentration in feces is associated to th...Continue Reading

Associated Datasets

References

Nov 1, 1991·Journal of Bacteriology·S J TruesdellR A Lazarus
Mar 1, 1991·The American Journal of Clinical Nutrition·T M WoleverH Eshuis
Oct 2, 2003·The Journal of Nutrition·Janet A Vogt, Thomas M S Wolever
Apr 22, 2004·The Proceedings of the Nutrition Society·Kevin WhelanMoira A Taylor
Oct 27, 2004·Proceedings of the National Academy of Sciences of the United States of America·Fredrik BäckhedJeffrey I Gordon
Apr 16, 2005·Science·Paul B EckburgDavid A Relman
Jan 31, 2006·The British Journal of Nutrition·A GostnerW Scheppach
Jun 3, 2006·Science·Steven R GillKaren E Nelson
Jun 20, 2006·Proceedings of the National Academy of Sciences of the United States of America·Buck S Samuel, Jeffrey I Gordon
Jul 6, 2006·Applied and Environmental Microbiology·T Z DeSantisG L Andersen
Oct 27, 2006·Human Genetics·Veronica L Martinez-MarignacEsteban J Parra
Nov 11, 2006·BMJ : British Medical Journal·Sarah H Wild, Christopher D Byrne
Nov 30, 2006·Current Opinion in Hematology·Kathrin S Michelsen, Moshe Arditi
Dec 22, 2006·Nature·Peter J TurnbaughJeffrey I Gordon
May 23, 2007·Anales de pediatría : publicación oficial de la Asociación Española de Pediatría (A.E.P.)·B García CuarteroE Díaz Martínez
Jun 28, 2007·PLoS Biology·Chana PalmerPatrick O Brown
Nov 21, 2007·Bulletin of the World Health Organization·Mercedes de OnisJonathan Siekmann
Mar 4, 2008·Journal of Internal Medicine·W P T James
Apr 3, 2008·Mayo Clinic Proceedings·John K DiBaiseBruce E Rittmann
Nov 14, 2008·Proceedings of the National Academy of Sciences of the United States of America·Noah FiererRob Knight
May 13, 2009·Proceedings of the National Academy of Sciences of the United States of America·Irma Silva-ZolezziGerardo Jimenez-Sanchez
Jun 6, 2009·The Journal of Physiology·Peter J Turnbaugh, Jeffrey I Gordon
Oct 24, 2009·The British Journal of Nutrition·Ramadass BalamuruganBalakrishnan S Ramakrishna
Nov 11, 2009·Current Opinion in Gastroenterology·Ruth E Ley
Apr 7, 2010·Science Translational Medicine·Peter J TurnbaughJeffrey I Gordon
Apr 13, 2010·Nature Methods·J Gregory CaporasoRob Knight
Aug 17, 2010·Bioinformatics·Robert C Edgar
Aug 31, 2011·F1000 Biology Reports·Michelle G Rooks, Wendy S Garrett
Oct 14, 2011·Journal of Clinical Gastroenterology·Harry J Flint
Feb 2, 2012·Archives of Medical Science : AMS·Nagwa Abdallah IsmailDina Fekry
Feb 7, 2012·Proceedings of the National Academy of Sciences of the United States of America·Torey LooftThad B Stanton
May 2, 2012·Obesity·Caroline L J KarlssonKristina Thorngren-Jerneck
Aug 2, 2012·Journal of Microbiological Methods·Andrew S WhiteleyAnthony O'Donnell
Aug 17, 2012·Nutrition Reviews·Luke K UrsellRob Knight
Sep 14, 2012·Nature·Valentina Tremaroli, Fredrik Bäckhed
Nov 30, 2012·The ISME Journal·Sebastian TimsErwin G Zoetendal
Feb 13, 2013·Clinical Chemistry·Sridevi DevarajJames Versalovic

❮ Previous
Next ❯

Citations

Mar 6, 2016·Microbial Ecology·Jaime García-MenaMaría Teresa Núñez-Cardona
Aug 15, 2015·Current Osteoporosis Reports·Julia E Inglis, Jasminka Z Ilich
Dec 3, 2017·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·Selvasankar MurugesanJaime García-Mena
Jun 10, 2016·Nature·Rachel J PerryGerald I Shulman
Jul 31, 2018·Current Diabetes Reviews·M E Romero-IbarguengoitiaAugusto Enrique Caballero
Dec 22, 2019·Nutrients·Kane E DeeringClaus T Christophersen
Feb 11, 2020·FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology·Nikhil S BhandarkarSunil K Panchal
Oct 23, 2019·Annual Review of Public Health·Audrey RensonJennifer B Dowd
Apr 23, 2020·Nutrients·Paulina Markowiak-Kopeć, Katarzyna Śliżewska
May 31, 2018·Endocrinology·Medha PriyadarshiniBrian T Layden
Jan 24, 2019·International Journal of Molecular Sciences·Alejandra Chávez-CarbajalCésar Hernández-Guerrero
Jun 28, 2019·Frontiers in Cellular and Infection Microbiology·Valentina MatteiSara Tomei
Jun 1, 2018·International Journal of Endocrinology·Olga CastanerHelmut Schröder
Nov 6, 2018·Nutrients·Andrea BrusaferroSusanna Esposito
May 21, 2019·The American Journal of Clinical Nutrition·Sophie HielNathalie M Delzenne
Jan 26, 2021·Journal of Alzheimer's Disease : JAD·Daniel Cuervo-ZanattaClaudia Perez-Cruz
Dec 15, 2020·Journal of Environmental Health Science & Engineering·Margarita Isabel Pérez-DíazClaudia Guerrero-Barajas
Feb 17, 2021·Obesity Reviews : an Official Journal of the International Association for the Study of Obesity·Kiley B Vander WystCorrie M Whisner
Apr 6, 2021·Frontiers in Endocrinology·Xin YuanKenneth L McCormick
Apr 23, 2021·Applied Microbiology and Biotechnology·Rongrong LiaoLihui Zhu
Aug 17, 2020·Journal of the Academy of Nutrition and Dietetics·Ana Maldonado-ContrerasKelsey M Mangano

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.