PMID: 18705522Aug 19, 2008Paper

Study of the influence of emotion stress on mechanical hyperalgesia of masseter muscles in rats

Hua xi kou qiang yi xue za zhi = Huaxi kouqiang yixue zazhi = West China journal of stomatology
Fei HuangJun Chen

Abstract

To study the influence of emotion stress on mechanical hyperalgesia of masseter muscles in rats through the equipment of communication box. 50 Sprague-Dawley rats were randomly divided into 5 groups: Control group, emotion stress (ES) group, drug control group, saline treated control group and footshock (FS) group, 10 rats each group. Footshock group only induced emotion stress and was not concerned with the result of the experiment. The last four groups of the rats were placed in communication box and bred under the same conditions during the experiment time. According to Rens' method, von Frey filaments were used to assess the muscle mechanical threshold, head withdrawal, leg raising and crying were observed as pain action. 1) During the adaptive period of 7 days before the emotion stress experiment, mechanical pain values of bilateral masseter muscles were descent and were stabilized in the 5 th to 7 th day. In emotion stress period, hyperalgesia of emotion stress group was induced in bilateral masseter muscles, and the peak time was the 7 th day, then it alleviated in the following days and was stabilized in the 12 th to 14 th day, but its pain threshold was lower than blank control group. 2)During the emotion stress period...Continue Reading

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