Study of the intramural oviduct response to tubal and uterine distension: identification of tubo-uterine sphincter and reflex

Human Reproduction
Ahmed Shafik

Abstract

The effect of tubal and uterine distension on the intramural portion of the oviduct (IMO) was studied in 11 women (mean age 31.1 years). The IMO length was determined and the pressure response of the IMO to distension of the anaesthetized oviduct and uterus was examined. A 1.2 cm long high pressure zone (32.2 +/- 6.9 cm H2O) was identified in the IMO. An IMO pressure drop occurred upon oviduct distension with 2 ml of CO2 (P < 0.01); distension with greater volumes induced the same pressure drop (not significant). The IMO pressure increased with 10 ml uterine distension (P < 0.05); distension with greater volumes did not induce further pressure rises (not significant). Distension of each of the anaesthetized oviduct, uterus and IMO separately effected no IMO pressure response. A 'tubo-uterine' physiological sphincter is postulated at the high pressure zone of the IMO. It relaxes or contracts upon tubal or uterine distension respectively. The sphincter response to tubal or uterine distension is suggested to occur by a reflex action through a 'tubo-uterine' reflex, as shown by reproducible results and sphincteric non-response upon anaesthetization of the two arms of the reflex.

Citations

Nov 2, 2004·Archives of Gynecology and Obstetrics·Ahmed ShafikIsmail Shafik
Sep 17, 2005·Archives of Gynecology and Obstetrics·Ahmed ShafikAli A Shafik
Nov 2, 2013·Animal Reproduction Science·Faviola Pedrero-BadilloEstela Cuevas
Jun 28, 2013·Journal of Ultrasound in Medicine : Official Journal of the American Institute of Ultrasound in Medicine·Yanni HeXiaohua Han
May 29, 2018·Folia primatologica; international journal of primatology·Alan F Dixson
Feb 6, 2017·Journal of Ultrasound in Medicine : Official Journal of the American Institute of Ultrasound in Medicine·Yanni HeHongmei Liu

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