Study of the relationships between brachytherapy plan parameters in an attempt to verify total dwell time in vaginal cylinder applications

Journal of Applied Clinical Medical Physics
Emmanuel Oyeyemi OyekunleMutiu A Jimoh

Abstract

Source strength (Sk ), sizes of vaginal cylinder applicators (VCA), number of dwell positions (DPs), and the prescribed dose (D) are basic parameters in brachytherapy (BT) treatment planning contributing to total dwell time (TDT). This study was aimed at assessing the relationships between the specified variables in an attempt to verify the TDT in high-dose-rate (HDR) vaginal cylinder applications. One hundred and twenty-one patients treated with Gynesource-Co60 (Bebig, Germany) using VCAs of diameters 20, 25, and 30 mm at University College Hospital, Nigeria, were enrolled in this study. Brachytherapy doses ranging from 3 to 7 Gy were always prescribed to points 5 mm away from the cylinder's surface. Treatment planning was undertaken on HDR-Basic treatment planning system (TPS) which utilizes source step size of 5 mm. Data on the stated parameters related to the first BT fractions of the patients were acquired. With the aid of EViews statistical software, two forms of mathematical models were thereafter developed. The resulting TDTs from the models were compared with the TPS values using Minitab statistical software. The relationships obtained for the increasing sizes of the VCA were TDT1(min)=2.22+3.17DSk;TDT1(min)=3.52+3.74D...Continue Reading

References

Apr 29, 1999·International Journal of Radiation Oncology, Biology, Physics·D J DemanesT Wong
Nov 1, 2001·Journal of Applied Clinical Medical Physics·C S Mayo, K Ulin
Jul 3, 2003·British Journal of Cancer·H WabingaD M Parkin
Oct 6, 2005·Gynecologic Oncology·Isaac F AdewoleMichele Follen
Jul 22, 2009·International Journal of Radiation Oncology, Biology, Physics·Akila N Viswanathan, Beth A Erickson

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Citations

Jun 17, 2021·Physics in Medicine and Biology·Jiawei FanYong Yang

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Methods Mentioned

BETA
hysterectomy

Software Mentioned

EViews

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