Study on carvacrol and cinnamaldehyde polymeric films: mechanical properties, release kinetics and antibacterial and antibiofilm activities.

Applied Microbiology and Biotechnology
Antonia NostroGiuseppe Bisignano

Abstract

Polyethylene-co-vinylacetate (EVA) films with different concentrations (3.5 wt% and 7 wt%) of essential oil constituents, carvacrol or cinnamaldehyde, were prepared and characterized by mechanical, antibacterial and antibiofilm properties. The incorporation of the compounds into copolymer films affected their elastic modulus, tensile stress and elongation at break. Carvacrol and cinnamaldehyde act as plasticizers which reduce the intermolecular forces of polymer chains, thus improving the flexibility and extensibility of the film. The analysis of the surface characteristics demonstrated that essential oil constituents lowered the contact angle values without causing any remarkable variation of the surface roughness. The films allowed progressive diffusion of the bioactive molecules and the kinetic of release was correlated with the damaging effect on bacterial growth. The kill curves proved that the film with essential oil constituents (7 wt%) had a significant bactericidal effect (reduction of 4 and 2 log CFU) against Staphylococcus aureus and Escherichia coli and a bacteriostatic effect against Staphylococcus epidermidis and Listeria monocytogenes (reduction of about 1 log CFU). With regard to biofilm formation the biomass fo...Continue Reading

References

Apr 1, 1986·Journal of Biomedical Materials Research·A H HogtJ Feijen
Mar 29, 2000·Journal of Applied Microbiology·H J Dorman, S G Deans
Feb 6, 2004·FEMS Microbiology Letters·Antonia NostroVittorio Alonzo
Jul 13, 2004·International Journal of Food Microbiology·Sara Burt
Sep 29, 2005·Antimicrobial Agents and Chemotherapy·Anna Rita BlancoDario Rusciano
Dec 24, 2005·Pharmaceutical Development and Technology·Elisabetta GaviniPaolo Giunchedi
Oct 13, 2006·Letters in Applied Microbiology·C NiuE S Gilbert
Mar 22, 2007·Journal of Medical Microbiology·Antonia NostroAnna Rita Blanco
May 29, 2007·Applied and Environmental Microbiology·Sara A BurtEdwin J A Veldhuizen
Sep 21, 2007·Journal of Agricultural and Food Chemistry·P LópezC Nerín
Feb 29, 2008·Journal of Biomedical Materials Research. Part a·Junhui Ji, Wei Zhang
Mar 13, 2008·Journal of Biomedical Materials Research. Part B, Applied Biomaterials·Roland R ArnoldSid Kalachandra
May 12, 2009·Journal of Medical Microbiology·Antonia NostroGiuseppe Bisignano
Aug 29, 2009·Journal of Agricultural and Food Chemistry·Laura GutiérrezCristina Nerín
Apr 24, 2010·Applied Microbiology and Biotechnology·Antonia NostroGiuseppe Bisignano
May 22, 2010·The Journal of Urology·Mary Anne Roshni AmalaradjouKumar Venkitanarayanan
Nov 1, 2009·Microbial Biotechnology·Antonio Di StefanoLuigina Cellini

❮ Previous
Next ❯

Citations

Oct 10, 2014·BioMed Research International·Abhinav UpadhyayKumar Venkitanarayanan
Jun 24, 2015·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Laura EspinaDiego García-Gonzalo
Jun 18, 2015·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Gaofeng YuanHaiyan Sun
Sep 25, 2015·Journal of Biomedical Materials Research. Part a·Anne Handrini DewiJohn Jansen
Oct 27, 2015·FEMS Microbiology Letters·Anna PapadopoulouTom Wiklund
Aug 5, 2014·International Journal of Food Microbiology·Laura HiguerasRafael Gavara
Dec 17, 2014·International Journal of Food Microbiology·Yong-Guy KimJintae Lee
Sep 25, 2014·Bioscience, Biotechnology, and Biochemistry·Ji-Hyun Lee, Kyung Bin Song
Jun 10, 2018·Letters in Applied Microbiology·J-H LeeJ Lee
Jul 13, 2018·Critical Reviews in Food Science and Nutrition·Nasreddine BenbettaïebThomas Karbowiak
Aug 8, 2020·Antibiotics·Hana Mohammed Al AlSheikhQazi Mohd Rizwanul Haq
Jul 17, 2018·Applied Microbiology and Biotechnology·Roberto ScaffaroAntonia Nostro
Dec 16, 2017·PloS One·Nathan ZaltsmanNurit Beyth
Jan 12, 2020·Applied Microbiology and Biotechnology·Roberto ScaffaroAntonia Nostro
Jun 18, 2016·Journal of Applied Biomaterials & Functional Materials·Roberto ScaffaroGiuseppe Gallo
Dec 10, 2019·International Journal of Pharmaceutics·Rafael Gomes Von BorowskiAline Rigon Zimmer

❮ Previous
Next ❯

Related Concepts

Related Feeds

Biofilm & Infectious Disease

Biofilm formation is a key virulence factor for a wide range of microorganisms that cause chronic infections.Here is the latest research on biofilm and infectious diseases.

Biofilms

Biofilms are adherent bacterial communities embedded in a polymer matrix and can cause persistent human infections that are highly resistant to antibiotics. Discover the latest research on Biofilms here.