PMID: 8606426Mar 1, 1996Paper

Study on characteristics of blast-fragment combined injury in dogs

The Journal of Trauma
J Z HuangH Leng

Abstract

It is known that blast wave and fragments are the primary causes of casualties from explosive weapons. To study the characteristics of blast-fragment combined injuries, functional and morphological changes were investigated in three groups of anesthetized dogs with blast injury, high velocity fragment extremity injury, and combined injuries of both types. The same parameters were also examined in a control group. Several of the functions investigated were systemic pressure, mean pulmonary arterial pressure (PAP), oxygenic partial pressure of arterial blood (Po2), thromboxane B2(TXB2), and 6-keto-prostaglandin F1 alpha (6-keto-PGF alpha). The morphologic study included gross, light microscopic, and transmission electronic microscopic observations. In the blast injury group, Po2 decreased and PAP, levels of blood plasma 6-keto-PGF alpha and level of TXB2 increased after injury, whereas PAP and level of 6-keto-PGF alpha decreased 24 hours after injury. The levels of 6-keto-PGF alpha and TXB2, in lung tissues, lung/body weight index were higher than those of the control group 24 hours after injury. The TXB2/6-keto-PGF alpha level in blood plasma increased slightly after injury, but showed no difference in lung tissue 24 hours after...Continue Reading

References

Feb 1, 1989·Journal of Applied Physiology·K YoshimuraL J Rubin
May 1, 1984·Proceedings of the Society for Experimental Biology and Medicine·A MolteniN H Solliday

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Citations

Jul 27, 1999·The Journal of Trauma·I CernakM Jevtic
May 15, 2003·Journal of the Royal Army Medical Corps·A J GibbonsS J Key

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