Study on compressive mechanical properties of nanohydroxyapatite reinforced poly(vinyl alcohol) gel composites as biomaterial.

Journal of Materials Science. Materials in Medicine
Yusong Pan, Dangsheng Xiong

Abstract

Nanohydroxyapatite reinforced poly(vinyl alcohol) (nano-HA/PVA) gel composites has been proposed as a promising biomaterial to replace diseased or damaged articular cartilage. In this paper, nano-HA/PVA gel composites were prepared by in situ synthesis nano-HA particles in PVA solution and accompanied with freeze/thaw method. The influence of nano-HA content, PVA concentration and freeze/thaw cycle times on the compressive mechanical behavior of nano-HA/PVA gel composites were evaluated using mechanical test equipment. The results showed that the compressive mechanical behavior of nano-HA/PVA gel composites was similar to that of natural articular cartilage, which held special viscoelastic characteristics. Both the compressive strength and modulus of the composites improved correspondingly with the rise of freeze/thaw cycle times and PVA concentration. The compressive strength and modulus of nano-HA/PVA gel composites firstly increased and then presented decreasing trend with the rise of nano-HA content. Furthermore, the compressive modulus of the composites improved exponentially with the rise of compressive strain ratio.

References

Jul 1, 1991·Journal of Applied Biomaterials : an Official Journal of the Society for Biomaterials·T NoguchiY Ikada
Dec 18, 2004·Biomaterials·Masanori KobayashiMasanori Oka

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Citations

Jan 30, 2014·PloS One·Timo AberleBurkhard Schlosshauer
Sep 28, 2012·Journal of Biomedical Materials Research. Part B, Applied Biomaterials·D Alves CardosoS C G Leeuwenburgh
May 10, 2016·Materials Science & Engineering. C, Materials for Biological Applications·Yan ShiXiaoduo Zhao
Jan 30, 2013·Journal of Biomedical Materials Research. Part B, Applied Biomaterials·Pan YusongWang Jing
Oct 27, 2018·Physics in Medicine and Biology·Sergio J SanabriaOrcun Goksel
Oct 28, 2013·Biomaterials Science·Changchun ZhouXingdong Zhang
Aug 1, 2018·Journal of Materials Science. Materials in Medicine·Shathani NkhwaSanjukta Deb
Aug 19, 2021·Journal of Materials Science. Materials in Medicine·Jie XieYihe Hu

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