Study on Large Deformation Behavior of Polyacrylamide Hydrogel Using Dissipative Particle Dynamics

Frontiers in Chemistry
Jincheng LeiZishun Liu

Abstract

Meso-scale models for hydrogels are crucial to bridge the conformation change of polymer chains in micro-scale to the bulk deformation of hydrogel in macro-scale. In this study, we construct coarse-grain bead-spring models for polyacrylamide (PAAm) hydrogel and investigate the large deformation and fracture behavior by using Dissipative Particle Dynamics (DPD) to simulate the crosslinking process. The crosslinking simulations show that sufficiently large diffusion length of polymer beads is necessary for the formation of effective polymer. The constructed models show the reproducible realistic structure of PAAm hydrogel network, predict the reasonable crosslinking limit of water content and prove to be sufficiently large for statistical averaging. Incompressible uniaxial tension tests are performed in three different loading rates. From the nominal stress-stretch curves, it demonstrated that both the hyperelasticity and the viscoelasticity in our PAAm hydrogel models are reflected. The scattered large deformation behaviors of three PAAm hydrogel models with the same water content indicate that the mesoscale conformation of polymer network dominates the mechanical behavior in large stretch. This is because the effective chains w...Continue Reading

References

Jan 1, 1981·Scientific American·T Tanaka
Nov 17, 2001·Chemical Reviews·K Y Lee, D J Mooney
Feb 26, 2009·The Journal of Physical Chemistry. B·Yanbin WuN R Aluru
Apr 3, 2012·Advanced Drug Delivery Reviews·Philipp S LienemannMartin Ehrbar
Sep 8, 2012·Nature·Kenneth R Shull
Sep 8, 2012·Nature·Jeong-Yun SunZhigang Suo
Dec 15, 2015·Materials Science & Engineering. C, Materials for Biological Applications·Santhosh MathesanPijush Ghosh
Jul 27, 2017·Nature Communications·Jinyao LiuGiovanni Traverso
Jul 29, 2017·Science·J LiD J Mooney
Nov 15, 2017·Advanced Materials·Lizhi XuNicholas A Kotov
Dec 1, 2016·Nature Reviews. Materials·Jianyu Li, David J Mooney
Apr 24, 2018·Soft Matter·Enrui ZhangZhigang Suo

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