Study on maternal, fetal, and amniotic human prolactin at term

The Journal of Clinical Endocrinology and Metabolism
V S Fang, M H Kim

Abstract

Prolactin present in maternal blood, fetal blood, and amniotic fluid samples obtained simultaneously at term was examined. The relative concentrations of prolactin in maternal and fetal serum samples were found to vary with each individual case. However, amniotic fluid samples contained a much higher level of prolactin than did both maternal and fetal serum samples in every case. After gel filtration, three separate peaks of immunoreactive prolactin were observed, probably representing three different sizes of the hormone molecule. The main component was small prolactin, constituting at least 69% of the total prolactin immunoreactivity in blood samples and 90% in amniotic fluids. Prolactin was found to be very similar in cord venous and arterial sera, both quantitatively and in terms of heterogeneity. There were more noticeable differences in the percentages of medium and small prolactin present in serum samples than in amniotic fluid samples. Big prolactin was present in all samples; its percentage in maternal serum was slightly higher than its percentages in the other samples. These results suggest that: 1) The mother and fetus carry on independent secretion of prolactin during gestation. 2) The size heterogeneity of prolacti...Continue Reading

Citations

Jan 1, 1989·Archives of Gynecology and Obstetrics·E OnurI Karslioğlu
Jul 1, 1982·Acta diabetologica latina·R M BottaG Bompiani
Jul 1, 1978·Irish Journal of Medical Science·O Lanigan, D Powell
Dec 1, 1976·Clinica Chimica Acta; International Journal of Clinical Chemistry·S Biswas
Aug 13, 1984·Life Sciences·R Dhanireddy, R E Ulane
Jan 9, 1992·European Journal of Obstetrics, Gynecology, and Reproductive Biology·C Castelo-BrancoJ González-Merlo
May 1, 1977·Molecular and Cellular Endocrinology·B Dattatreyamurty, A R Sheth
Jun 1, 1978·Molecular and Cellular Endocrinology·D L HealyH K Muller
Apr 1, 1978·Psychoneuroendocrinology·A E Boyd, S Reichlin
Jan 1, 1978·Clinical Endocrinology·A R GenazzaniR Corda
Dec 1, 1979·The Journal of Clinical Investigation·D S CooperF Maloof
Sep 15, 1985·American Journal of Obstetrics and Gynecology·J A McCoshen, J Barc
Aug 1, 1982·International Journal of Gynaecology and Obstetrics : the Official Organ of the International Federation of Gynaecology and Obstetrics·K BremmeB Nilsson
Jan 1, 1986·Clinical Endocrinology·M L MitchellE L Mitchell
Mar 1, 1982·Clinical Endocrinology·Y K SoongS L Jeffcoate
Nov 15, 1980·American Journal of Obstetrics and Gynecology·S M RosenbergD H Riddick
May 1, 1984·The Australian & New Zealand Journal of Obstetrics & Gynaecology·D L Healy
May 1, 1977·The Australian & New Zealand Journal of Obstetrics & Gynaecology·D L Healy, H G Burger
Jan 1, 1990·Journal of Sex & Marital Therapy·R C Schiavi
Jul 1, 1979·Journal of Endocrinological Investigation·W D LehmannA S Wolf
Jun 1, 1989·Asia-Oceania Journal of Obstetrics and Gynaecology·M ShaarawyR A Ezzat
Jun 1, 1984·Asia-Oceania Journal of Obstetrics and Gynaecology·T KubotaM Saito
Apr 1, 1981·Journal of Endocrinological Investigation·A D RogolS W Rosen
May 1, 1985·Annals of Clinical Biochemistry·H Z WangS L Jeffcoate
Nov 9, 1978·Life Sciences·D H RiddickI A Maslar
May 27, 1977·Biochimica Et Biophysica Acta·P RathnamB B Saxena
Jun 1, 1978·Metabolism: Clinical and Experimental·N J OlsenL J DeGroot

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