PMID: 3759149Jun 1, 1986Paper

Study on the association of HLA with pulmonary tuberculosis

Immunological Investigations
X P XuQ H Li

Abstract

The association between HLA and pulmonary tuberculosis was investigated in 50 Chinese patients. The frequencies of the HLA-A11 and -B15 antigens were increased (P less than 0.025) in patient group. Relative risks (R.R.) were 2.13 and 2.39, respectively. In contrast, the frequency of the HLA-Cw3 antigen and the R.R. (0.29) were decreased (P less than 0.005) in the patient group. These results are different from those reported by other researchers for Caucasian and Chinese tuberculosis patients. Moreover, it was found that the frequency of the A11-B15 haplotype in all patients with cavitation was 3-4 times higher (P less than 0.01) than in control individuals. The R.R. was 3.57.

References

Jan 1, 1985·The Journal of Infectious Diseases·M S Pollack, R R Rich
Jul 1, 1983·Tissue Antigens·Z F JiangT D Lee

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Citations

Jan 1, 1997·Emerging Infectious Diseases·N SinghA K Rastogi
Oct 1, 1992·Tubercle and Lung Disease : the Official Journal of the International Union Against Tuberculosis and Lung Disease·C B SanjeeviO Olerup
Dec 13, 2018·Ear, Nose, & Throat Journal·Kai-Chieh ChanPing-Chin Lai

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