PMID: 6970155Jan 1, 1980Paper

Study on the effects of L-5HTP on the stages of sleep in man as evaluated by using sleep deprivation

Folia Psychiatrica Et Neurologica Japonica
Y NakazawaK Dainoson

Abstract

The effects of L-5HTP 200 mg on the EEG sleep pattern were investigated in normal subjects. When L-5HTP 200 mg was orally administered, only % S1 significantly decreased in comparison with the baseline. There was no change in any sleep stage on the first recovery night. On the second recovery night, % S1 significantly decreased, while % SR increased significantly. SWS did not show any change. The effects of L-5HTP 200 mg were investigated on the first recovery night after one night of sleep deprivation. SWS significantly increased on the first recovery night when a placebo was given, while this rebound increase of SWS disappeared and % S2 significantly increased on the first recovery night when L-5HTP was given. % SR significantly increased on the next night after the L-5HTP night.

References

Jun 1, 1971·Electroencephalography and Clinical Neurophysiology·R J WyattA Sjoerdsma
Jan 3, 1969·Science·M Jouvet
Jan 1, 1971·Psychopharmacologia·J D CoulterH L Williams
Aug 1, 1968·American Journal of Public Health and the Nation's Health·L Shatin
Apr 1, 1966·The British Journal of Psychiatry : the Journal of Mental Science·I OswaldV R Thacore
Jan 1, 1966·Psychopharmacologia·E Hartmann

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Citations

Dec 1, 1986·Pediatric Annals·J Puig-Antich
Jul 21, 2015·BJPsych Bulletin·Thomas J Reilly
Jul 1, 1983·AORN Journal·F L Ulschak, J K Hixon
Jan 1, 1994·Occupational and Environmental Medicine·R KishiH Sasatani

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