Study on the polymorphism of bovine lactoferrin gene and its relationship with mastitis

Animal Biotechnology
Guo-Hua LiNing Li

Abstract

Mastitis is a major cause of economic loss to the dairy industry. Lactoferrin (Lf) is known to contribute to resistance against bacterial infections. Hence, we decided to characterize the relevance between mastitis resistance and the variants of Lf gene. By using PCR-SSCP, five fragments within 5' region and all exons of bovine lactoferrin gene were amplified and identified the nucleotide diversity. For the five segments within the 5'-region: Lf5'-1, Lf5'-2, Lf5'-3, Lf5'-4, and Lf5'-5 from upstream to downstream, we found that three had base variation. Totally, mutations were observed in Lf5'-1, Lf5'-3, and Lf5'-5, exons 4, 8, 9, 11, 15, and intron 4. We analyzed the effects of all mutated loci on milk production traits with least squares method.

References

May 1, 1992·Archives of Disease in Childhood·L SánchezJ H Brock
Jan 1, 1990·Journal of Dairy Science·S TsujiS Ohtagaki
Sep 1, 1970·Journal of Dairy Science·J J Janzen
Nov 1, 1980·Journal of Dairy Science·S N GauntB A Mitchell
Jul 1, 1994·Journal of Dairy Science·R J Harmon
Feb 1, 1994·Journal of Dairy Science·G E Shook, M M Schutz
Apr 10, 2003·The Veterinary Clinics of North America. Food Animal Practice·Rubén N González, David J Wilson
Oct 22, 2003·Biochemistry and Cell Biology = Biochimie Et Biologie Cellulaire·Tetsuya TanakaKei-ichi Shimazaki

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Citations

Apr 20, 2006·Animal Biotechnology·M DalyF Buckley
Feb 3, 2015·Polish Journal of Veterinary Sciences·T ZabolewiczS Kamiński
Apr 25, 2009·Journal of Dairy Science·V M-R ArnouldR Renaville
Jan 22, 2019·Reproduction in Domestic Animals = Zuchthygiene·Wael B El-DomanySherif M Nasr
Dec 17, 2009·Tropical Animal Health and Production·Periasamy KathiravanNeetu Tyagi

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Methods Mentioned

BETA
PCR

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