Study Probes Burkitt Lymphoma-Malaria Link

Cancer Discovery

Abstract

Burkitt lymphoma is unusually common in parts of Africa where malaria is widespread, but the reason for the association has been unclear. A new study suggests that parasitic infection triggers dramatic B-cell proliferation and increased expression of the enzyme activation-induced cytidine deaminase, which generates more potent antibodies-and causes mutations that lead to cancer.

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Antimalarial agents, also known as antimalarials, are designed to prevent or cure malaria. Discover the latest research on antimalarial agents here.