Study protocol of the German "Registry for the detection of late sequelae after radiotherapy in childhood and adolescence" (RiSK).

Radiation Oncology
Tobias BöllingNormann Willich

Abstract

Late effects after radiotherapy in childhood and adolescence have mainly been characterized retrospectively with small patient numbers. However, these analyses are limited due to little information regarding organ dose levels in many cases. To overcome this limitation, the German Group of Paediatric Radiation Oncology (APRO) established the "Registry for the evaluation of late side effects after radiation in childhood and adolescence" (RiSK). The study protocol and the documentation forms are given in this publication. Radiation parameters including detailed organ doses as well as toxicity evaluations are collected prospectively from centres all over Germany. Standardized documentation forms are used. These forms are given in an English and German version as additional files to this publication. Documentation is planned for all children who receive radiotherapy in one of the therapy trials of the "German Society of Paediatric Oncology and Haematology (GPOH)". The study started in a pilot phase in June 2001 in few centres. Since 2004 documentation has been performed all over Germany and is still on-going. To our knowledge, "RiSK" is the only multi-centre study that evaluates radiation associated side effects prospectively with d...Continue Reading

References

Jan 1, 1990·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·N J TarbellH J Weinstein
Mar 30, 1995·International Journal of Radiation Oncology, Biology, Physics·J D CoxT F Pajak
Jun 1, 1994·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·M FlentjeR Ludwig
Jan 5, 2001·Strahlentherapie und Onkologie : Organ der Deutschen Röntgengesellschaft ... [et al]·M FussE B Hug
Feb 18, 2004·Pediatric Blood & Cancer·Thorsten LangerUNKNOWN German Late Effects Working Group in the German Society of Pediatric Oncology and Hematology
Jul 27, 2005·Strahlentherapie und Onkologie : Organ der Deutschen Röntgengesellschaft ... [et al]·Andreas SchuckNormann Willich
Sep 20, 2005·Strahlentherapie und Onkologie : Organ der Deutschen Röntgengesellschaft ... [et al]·Günther GruberRichard H Greiner
Aug 10, 2006·Strahlentherapie und Onkologie : Organ der Deutschen Röntgengesellschaft ... [et al]·Tobias BöllingNormann Willich
Oct 13, 2006·The New England Journal of Medicine·Kevin C OeffingerUNKNOWN Childhood Cancer Survivor Study
Jan 18, 2008·Strahlentherapie und Onkologie : Organ der Deutschen Röntgengesellschaft ... [et al]·Tobias BöllingNormann Willich

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Citations

Aug 25, 2009·Strahlentherapie und Onkologie : Organ der Deutschen Röntgengesellschaft ... [et al]·Normann WillichTobias Bölling
Mar 15, 2016·International Journal of Radiation Oncology, Biology, Physics·Caroline PixbergDiana Steinmann
Jul 20, 2010·International Journal of Radiation Oncology, Biology, Physics·Tobias BöllingNormann Willich
Jul 8, 2010·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·Nadja SeloNormann Willich
Jun 15, 2014·Journal of Cancer Survivorship : Research and Practice·Irma W E M van DijkLeontien C M Kremer
Dec 10, 2014·Strahlentherapie und Onkologie : Organ der Deutschen Röntgengesellschaft ... [et al]·Pascal RöslerDiana Steinmann
Jan 4, 2020·World Journal of Surgery·Margaret J TarpleyJohn L Tarpley

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RiSK

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