Studying posttranslational modifications by in-cell NMR

Chemistry & Biology
Guy LippensX Hanoulle

Abstract

Functional in vivo investigation of posttranslational modifications is a problem that a number of analytical techniques are trying to tackle. Below, we briefly discuss the breakthroughs and challenges in placing NMR spectroscopy on the map, as illustrated by a recent report by Selenko et al. (2008).

References

Aug 1, 1996·Nature Structural Biology·A A RussoN P Pavletich
Dec 22, 1999·The EMBO Journal·B van den BergC M Dobson
Jul 18, 2001·Journal of the American Chemical Society·Z SerberV Dötsch
Sep 25, 2002·Proceedings of the National Academy of Sciences of the United States of America·Matthew M DedmonGary J Pielak
Nov 4, 2005·Angewandte Chemie·Christopher T WalshGregory J Gatto
Mar 16, 2006·Journal of the American Chemical Society·Isabelle LandrieuGuy Lippens
Jul 29, 2006·Proceedings of the National Academy of Sciences of the United States of America·Philipp SelenkoGerhard Wagner
Oct 13, 2006·Journal of Biomolecular NMR·Tomomi SakaiMasahiro Shirakawa
Feb 26, 2008·Nature Structural & Molecular Biology·Philipp SelenkoGerhard Wagner
Feb 27, 2008·Biochemical and Biophysical Research Communications·Vanessa DehennautTony Lefebvre

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Citations

Sep 27, 2012·Journal of Biomolecular NMR·Francois-Xavier TheilletPhilipp Selenko
Aug 1, 2014·Nature Protocols·Isabella C FelliRoberta Pierattelli
Aug 31, 2010·Current Opinion in Structural Biology·Yutaka Ito, Philipp Selenko
Nov 28, 2012·Current Opinion in Chemical Biology·Hidehito Tochio
Feb 26, 2011·Angewandte Chemie·Ivano BertiniRoberta Pierattelli

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