Studying the genetic basis of speciation in high gene flow marine invertebrates

Current Zoology
Grant H Pogson

Abstract

A growing number of genes responsible for reproductive incompatibilities between species (barrier loci) exhibit the signals of positive selection. However, the possibility that genes experiencing positive selection diverge early in speciation and commonly cause reproductive incompatibilities has not been systematically investigated on a genome-wide scale. Here, I outline a research program for studying the genetic basis of speciation in broadcast spawning marine invertebrates that uses a priori genome-wide information on a large, unbiased sample of genes tested for positive selection. A targeted sequence capture approach is proposed that scores single-nucleotide polymorphisms (SNPs) in widely separated species populations at an early stage of allopatric divergence. The targeted capture of both coding and non-coding sequences enables SNPs to be characterized at known locations across the genome and at genes with known selective or neutral histories. The neutral coding and non-coding SNPs provide robust background distributions for identifying FST-outliers within genes that can, in principle, identify specific mutations experiencing diversifying selection. If natural hybridization occurs between species, the neutral coding and no...Continue Reading

References

Jun 20, 1991·Nature·J H McDonald, M Kreitman
Jun 22, 1993·Proceedings. Biological Sciences·A Eyre-Walker
Apr 12, 2001·Molecular Ecology·N H Barton
Jul 27, 2001·Molecular Biology and Evolution·M AnisimovaZ Yang
Dec 26, 2001·Science·H C SeoD Chourrout
Oct 29, 2004·Bioinformatics·Sergei L Kosakovsky PondSpencer V Muse
Feb 18, 2005·Genetics·Joachim Hermisson, Pleuni S Pennings
Jul 13, 2005·Molecular Phylogenetics and Evolution·Michelle T GuzikRoss H Crozier
Aug 4, 2005·PLoS Biology·Thomas L TurnerSergey V Nuzhdin
Jan 3, 2006·Reproduction : the Official Journal of the Society for the Study of Fertility·Nathaniel L ClarkWillie J Swanson
Oct 13, 2006·Nature Reviews. Genetics·Mohamed A F Noor, Jeffrey L Feder
Nov 11, 2006·Science·Erica SodergrenRita Wright
May 8, 2007·Molecular Biology and Evolution·Ziheng Yang
Jul 21, 2007·BMC Evolutionary Biology·Markus Pfenninger, Klaus Schwenk
Nov 13, 2007·Nature·UNKNOWN Drosophila 12 Genomes ConsortiumIain MacCallum
Jun 5, 2008·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·Roger K ButlinJohn W Grahame
Jun 20, 2008·Nature·Nicholas H PutnamDaniel S Rokhsar
Aug 2, 2008·PLoS Genetics·Carolin KosiolAdam Siepel
Aug 23, 2008·Nature·Mansi SrivastavaDaniel S Rokhsar
Oct 15, 2008·PloS One·Nathan A BairdEric A Johnson
Jan 16, 2009·Molecular Ecology·Patrik NosilDaniel Ortiz-Barrientos
Feb 7, 2009·Science·Dolph Schluter
Feb 27, 2009·Molecular Ecology·Zachariah Gompert, C Alex Buerkle
Sep 8, 2009·Journal of Evolutionary Biology·B M FitzpatrickS Gavrilets
Oct 3, 2009·Evolution; International Journal of Organic Evolution·Katherine C TeeterPriscilla K Tucker
Oct 20, 2009·Genome Biology·Ryan TewheyKelly A Frazer
Oct 30, 2009·International Journal of Molecular Sciences·Michael L Arnold, Nicole D Fogarty
Dec 17, 2009·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·Taras K OleksykStephen J O'Brien
Jan 7, 2010·Nature Reviews. Genetics·Daven C Presgraves
Jan 30, 2010·Nature Methods·Lira MamanovaDaniel J Turner
Feb 25, 2010·Current Biology : CB·Jonathan K PritchardGraham Coop
May 8, 2010·Molecular Biology and Evolution·William Fletcher, Ziheng Yang
Jun 26, 2010·Annals of Botany·Loren H Rieseberg, Benjamin K Blackman

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Citations

Mar 27, 2021·Biological Reviews of the Cambridge Philosophical Society·Tania Hernández-HernándezJohn J Wiens
Apr 7, 2021·Genome Biology and Evolution·Yutaka SatouNoriyuki Satoh
Jul 27, 2021·Molecular Biology and Evolution·Shotaro HiraseKiyoshi Kikuchi

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