PMID: 6414114Aug 1, 1983Paper

Styrene oxidation to styrene oxide coupled with arachidonic acid oxidation by soybean lipoxygenase

Toxicology Letters
G BelvedereH Vainio

Abstract

Styrene was co-oxidated to styrene oxide during soybean lipoxygenase catalyzed formation of arachidonic acid lipid peroxides. Styrene oxidation showed linear dependence on the amount of enzyme and on arachidonic acid concentration, and saturation kinetics with styrene concentration. Styrene oxide formation was dependent on the lipid substrate used and was inhibited by antioxidants. Lipid peroxides appear to be able to support styrene oxidation when produced from rat liver microsomes.

References

Oct 1, 1976·Xenobiotica; the Fate of Foreign Compounds in Biological Systems·M SalmonaS Garattini
Nov 1, 1978·Mutation Research·K LinnainmaaH Vainio
Jan 1, 1980·Proceedings of the National Academy of Sciences of the United States of America·M I SiegelP Cuatrecasas
Sep 30, 1982·Biochemical and Biophysical Research Communications·T WatabeA Tsubaki

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Citations

Nov 1, 1991·Mutation Research·D D BrennerF P Perera
Mar 1, 1997·Toxicology and Applied Pharmacology·A P Kulkarni, M P Sajan
Feb 1, 1991·Research Communications in Chemical Pathology and Pharmacology·A K Naidu, A P Kulkarni
Jan 1, 1985·Critical Reviews in Toxicology·P H Bach, J W Bridges
Jan 1, 1985·CRC Critical Reviews in Toxicology·P H Bach, J W Bridges
Aug 1, 1995·Xenobiotica; the Fate of Foreign Compounds in Biological Systems·A P Kulkarni, K R Murthy
Jan 1, 1994·Critical Reviews in Toxicology·S J Sumner, T R Fennell
Apr 1, 1994·Prostaglandins, Leukotrienes, and Essential Fatty Acids·K A Akhilender NaiduA P Kulkarni
Apr 1, 1987·Archives of Biochemistry and Biophysics·E Blee, F Durst

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