SU-D-211-02: A Framework for 4pi Radiotherapy

Medical Physics
Ke ShengDan Ruan

Abstract

Inclusion of highly non-coplanar treatment angles increases radiations dose conformality and critical organ sparing. However, implementation of this treatment strategy has been hampered by inaccurate solution space modeling, limited automated beam selection methods, the lack of efficient beam sequencing program and integrated collision prevention. The aim is to develop a 4pi radiotherapy paradigm that takes full advantage of modern computer-controlled robotic C-arm linear accelerators. The beam geometry solution space was modeled by 3D surface scanning of the couch, gantry and patient. In order to utilize the entire solution space and optimize MLC resolution, variable source-to-tumor distances were introduced. Conformai radiation doses were computed using convolution/superposition from uniformly distributed solid angles. Beam orientation optimization was performed using a column generation and pricing approach, which was also used to optimize beam fluence intensity modulation. A level set method was then employed to automatically sequence beams so the treatment time and couch motion can be minimized while avoiding collision on the path. The machine and patient surface was accurately measured and a cocoon shaped solution space w...Continue Reading

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