SU-E-I-31: Evaluating Brain Imaging Material (BIM) as a Brain Tissue Surrogate for Use in Neuro-Endovascular Imaged Guided Intervention (EIGI) Research

Medical Physics
B LoughranS Rudin

Abstract

A brain tissue surrogate material was needed to fill the anatomical cavity of a skull to create a phantom for use in simulated Neuro-EIGI procedures. To enable diagnostic and interventional procedure simulation, the BIM must fit into and be congruous with the interior surface of the skull, be reusable, and allow the implantation of vascular phantoms. The material must reasonably reproduce the automatic technique parameter selections observed during Neuro-EIGI procedures. We formulated a putty- like material to be used as the BIM. Its x-ray attenuation properties were evaluated by comparison of the fluoroscopic and radiographic technique parameters automatically selected for a BIM-filled skull on a Toshiba Infinix angiographic C-arm unit to those of a solid anthropomorphic head phantom at various projection angles. The same comparison was made between the skull phantom without BIM in the cavity and the anthropomorphic head phantom. The BIM linear attenuation coefficient was calculated and compared to that of PMMA, a common tissue analog plastic. The BIM keeps its shape, is moldable and reusable, and is congruent to the skull's interior surfaces. It allows for insertion and interchange of various custom vascular phantoms at prope...Continue Reading

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.