SU-E-T-101: Dosimetry Intercomparison for a Synchrotron-Produced Monochromatic X-Ray Beam

Medical Physics
Tad BrownKenneth L Matthews

Abstract

This study performed a dosimetry intercomparison for synchrotron-produced monochromatic x-ray beams. Ion chamber depth-dose measurements in a polymethylmethacrylate (PMMA) phantom were compared with the product of MCNP5 Monte Carlo calculations of dose per fluence and measured incident fluence at 25 and 35 keV. The ion chamber measurements are being used to calibrate dose output for cell irradiations designed to investigate photoactivated Auger electron therapy at the LSU Center for Advanced Microstructures and Devices (CAMD) synchrotron facility. Monochromatic beams of 25 and 35 keV were generated on the tomography beamline at CAMD. A cylindrical, air-equivalent ion chamber was used to measure the ionization created in a 10×10×10-cm(3) PMMA phantom at depths of 0.6 - 7.7 cm. AAPM TG-61 protocol was applied to convert measured ionization into dose. MCNP5 simulations of the irradiation geometry were performed to determine the dose deposition per photon fluence in the phantom. Photon fluence was determined using a NaI detector to make scattering measurements of the beam from a polyethylene target at angles 15 - 60 degrees. Differential Compton and Rayleigh scattering cross sections were used to derive the incident fluence. At 35 ...Continue Reading

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