SU-E-T-272: Commissioning an Orthovoltage Unit Used for Radiobiology Research

Medical Physics
Rezvan AzimiSusanta K Hui

Abstract

Orthovoltage X-ray units are used to irradiate cell cultures or small animals in research. Beam characteristics of these units are often not well understood and only nominal dose specified is used by researchers in their studies. This work describes commissioning of an orthovoltage unit similar to that of a linear accelerator. The X-Rad 320 Orthovoltage unit is a self-contained x-ray system which can be operatedwithin a wide range of kVp and mAs settings. This work characterizes the beam produced by this system. Various beam data, including depth dose, cross profiles, collimator and total scatter factors, have been measured. Collimator and total scatter measurements were done with cylindrical farmer chambers (0.6 cc and 0.057 cc volumes) for field sizes ranging from 2×2 to 20×20 cm(2) . Sc measurements were done in air at 50 cm SCD and Sc,p measurements were done in 2 cm depth of phantom at 50 cm SSD.The depth dose curves were generated for three different field sizes for depths up to 15 cm. A parallel plate chamber was used for surface and near surface dose measurements while the cylindrical chamber was used for other depths. Measurements of Sc and Sc,p indicate minimal variation of these factors with field size, except for ve...Continue Reading

Citations

Jan 11, 2020·FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology·Panshak P DakupShobhan Gaddameedhi

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.