SU-E-T-282: Preliminary Simulation Study for 3 Dimensional Dose Delivery in Carbon Beam Active Scanning System of KHIMA

Medical Physics
C KimS Hong

Abstract

KHIMA (Korea Heavy Ion Medical Accelerator) project has a plan to develop and construct a research beam line for carbon beam active scanning system. The carbon beam line consists with scanning magnet, beam-monitoring system, energy modulation system. In this study, the significant components, scanning magnets and ridge filter, were designed for the carbon beam active scanning beam line. The designed scanning magnet and ridge filter were used for 3 dimensional active beam dose delivery simulation by Geant4 Monte Carlo code. The target volume of the active scanning was 10 × 10 × 5 cm(2) on the water phantom with 400 MeV/u of carbon beam. The transvers plane on the target was scanned by 3mm of step size. And, the optimized weighting factors of transverse scanning were obtained by MINUIT fitting package of ROOT. An aluminum ridge filter was designed to generate 5 cm of physical SOBP through step shape, which was optimized through in-house iteration method and the MINUIT package.The simulation was performed with Geant4 through applying the transverse scanning with the obtained weighting factor and the designed ridge filter. The uniformity on the transverse plan will be expected below 4% when it considered scattered beam. Also, the u...Continue Reading

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.