Sub-National Targeting of Seasonal Malaria Chemoprevention in the Sahelian Countries of the Nouakchott Initiative

PloS One
Abdisalan M NoorR W Snow

Abstract

Seasonal malaria chemoprevention (SMC) has been shown to be highly efficacious against clinical malaria in areas where transmission is acutely seasonal. SMC targeting depends on a complex interplay of climate, malaria transmission and population distribution. In this study a spatial decision support framework was developed to identify health districts suitable for the targeting of SMC across seven Sahelian countries and northern states of Nigeria that are members of the Nouakchott Initiative. A spatially explicit decision support framework that links information on seasonality, age-structured population, urbanization, malaria endemicity and the length of transmission season was developed to inform SMC targeting in health districts. Thresholds of seasonality, population and receptive risks were defined to delineate SMC suitable health districts and define the age range of children for targeting. Numbers of children were then computed for the period 2015-2020 in SMC districts. For 2015, this was combined with maps of length of malaria transmission seasons and WHO recommended treatment regimen to quantify the number of tablets required across the SMC health districts. A total of 597 Sahelian health districts were mapped, out of wh...Continue Reading

References

Jan 11, 2003·Advances in Parasitology·Robert W Snow, Kevin Marsh
Oct 2, 2003·Trends in Parasitology·Lorenz von Seidlein, Brian M Greenwood
Dec 5, 2003·Lancet·Frank C TanserDavid le Sueur
Dec 21, 2004·Nature Reviews. Microbiology·Simon I HayRobert W Snow
May 13, 2006·Malaria Journal·Emily K Grover-KopecStephen J Connor
Aug 8, 2008·Geospatial Health·Stephen J ConnorMadeleine C Thomson
May 7, 2009·Malaria Journal·Khadijetou Mint LekweiryAli Ould Mohamed Salem
Nov 5, 2011·Malaria Journal·Nathalie WurtzSébastien Briolant
Nov 5, 2011·Malaria Journal·Michael T WhiteAzra C Ghani
Dec 12, 2012·Malaria Journal·Maria BernabeuOgobara Doumbo
Nov 7, 2013·Malaria Journal·Deepa K PindoliaAndrew J Tatem

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Citations

Jan 15, 2017·Malaria Journal·Jeremy N BurrowsTimothy N C Wells
Nov 23, 2016·PLoS Medicine·Robert W Snow
Dec 21, 2017·The American Journal of Tropical Medicine and Hygiene·Thomas DruetzSlim Haddad
Aug 5, 2017·Nature Reviews. Disease Primers·Margaret A PhillipsTimothy N C Wells

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