Abstract
The present study examined the ability of dual-chamber (DDD) pacing to improve symptoms and exercise tolerance in patients with non-obstructive hypertrophic cardiomyopathy (HNCM). Seven patients with HNCM who had failed to benefit from pharmacotherapy participated in the study. The New York Heart Association (NHYA) functional class status and exercise tolerance, which was determined by the treadmill exercise test, were recorded and an echocardiographic observation was performed before, and 1 week, 3 months and 1 year after the implantation of a permanent DDD pacemaker. The atrioventricular delay (AVd) was determined by measuring the point of peak rapid filling velocity and maximum cardiac output (CO). Two patients were not implanted with a permanent pacemaker because their CO and blood pressure decreased or because palpitation occurred during temporary pacing. The ratio between early and late peaks of flow velocity (1.56, 1.21,0.95, and 0.86 before implantation and 1 week, 3 months and 1 year after implantation, respectively); deceleration time (ms: 263.2, 217.6, 204.6, 187.0); peak filling rate (ml/s: 146.2, 204.0, 233.2, 243.6); NYHA functional class status (2.0, 1.8, 1.6, 1.4); and exercise tolerance (s: 203, 264, 403, 480) ...Continue Reading
References
Mar 1, 1979·Japanese Circulation Journal·I SotobataJ Tsuzuki
Dec 1, 1978·The American Journal of Cardiology·M J FrankR E Saylors
Jun 1, 1979·The American Journal of Cardiology·B J Maron, S E Epstein
Dec 1, 1979·Circulation·D R RosingS E Epstein
Dec 1, 1978·Circulation·D J SahnA Weyman
Oct 1, 1975·Thoraxchirurgie, Vaskuläre Chirurgie·P HassensteinW Schmitz
Jan 1, 1976·The American Journal of Cardiology·L E TeichholzR Gorlin
May 30, 1992·Lancet·X JeanrenaudL Kappenberger
Jun 1, 1992·Circulation·L FananapazirJ A Panza
Aug 8, 1992·Lancet·P H SeidelinN A Boon
Sep 11, 1992·The American Journal of Cardiology·L H CohnJ J Collins
May 1, 1990·Journal of the American College of Cardiology·J L VanoverscheldeJ R Cosyns
Aug 1, 1988·European Heart Journal·K McDonaldB Maurer
Oct 1, 1987·Journal of the American College of Cardiology·B J MaronJ Arce
Mar 1, 1986·Journal of the American College of Cardiology·P SpiritoR O Bonow
Jan 1, 1982·Japanese Circulation Journal·A KitabatakeH Matsuo
Nov 1, 1995·Journal of the American College of Cardiology·M MiyagawaK Hamamoto
Jul 22, 1995·Lancet·U Sigwart
Mar 15, 1994·The American Journal of Cardiology·R O CannonL Fananapazir
Feb 1, 1996·Journal of the American College of Cardiology·R A NishimuraA J Tajik
Oct 7, 1997·Circulation·M HamadaK Hiwada