Subacute chlordane poisoning

Journal of Toxicology. Clinical Toxicology
L K GarrettsonR V Blanke

Abstract

A 30 year old female was exposed to chlordane through careless and excessive domestic use over a 1 to 4 week period. Early symptoms included circumoral numbness, anorexia, nausea, and fatigue. Myoclonic jerks occurred after a delay of one month. Malaise and anorexia became the dominant symptoms leading to referral at six months. Dysfunctional bleeding was attributed to hepatic enzyme induction by the chlordane and increased metabolism of contraceptive medication. Cholestyramine increased the stool elimination of chlordane.

References

Feb 2, 1978·The New England Journal of Medicine·W J CohnP S Guzelian
Apr 19, 1976·JAMA : the Journal of the American Medical Association·B Furie, S Trubowitz
Feb 1, 1969·Archives of Environmental Health·A Curley, L K Garrettson

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